Evidence map›Paper›PMID 26316206›Full record

ArticleBMC veterinary research2015

International Veterinary Epilepsy Task Force's current understanding of idiopathic epilepsy of genetic or suspected genetic origin in purebred dogs.

Velia-Isabel Hülsmeyer, Andrea Fischer, Paul J J Mandigers, Luisa DeRisio, Mette Berendt, Clare Rusbridge, Sofie F M Bhatti, Akos Pakozdy, Edward E Patterson, Simon Platt and 2 more

Abstract read
In one paragraph

Article in BMC veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Article
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  8. Article
  9. Article
  10. Effects ofVeterinary sciences · 2025
    Article
  11. Article
  12. Article
  13. Exploring Gut Microbiota-Targeted Therapies for Canine Idiopathic Epilepsy.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Ethical Concerns about Fashionable Dog Breeding.Animals : an open access journal from MDPI · 2024
    Review
  19. Article
  20. Electroencephalography: electrode arrays in dogs.Frontiers in veterinary science · 2024
    Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Velia-Isabel HülsmeyerCentre for Clinical Veterinary Medicine, Ludwig-Maximilians-University, Veterinärstr. 13, 80539, Munich, Germany. v.huelsmeyer@medizinische-kleintierklinik.de.
Andrea FischerCentre for Clinical Veterinary Medicine, Ludwig-Maximilians-University, Veterinärstr. 13, 80539, Munich, Germany. andreafischer@lmu.de.
Paul J J MandigersDepartment of Clinical Sciences of Companion Animals, Utrecht University, Yalelaan 108, 3583 CM, Utrecht, The Netherlands. P.J.J.Mandigers@uu.nl.
Luisa DeRisioAnimal Health Trust, Lanwades Park, Kentford, Newmarket, CB8 7UU, Suffolk, United Kingdom. luisa.derisio@aht.org.uk.
Mette BerendtDepartment of Veterinary and Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark. mbe@sund.ku.dk.
Clare RusbridgeFitzpatrick Referrals, Halfway Lane, Eashing, Godalming, GU7 2QQ, Surrey, United Kingdom. ClareR@fitzpatrickreferrals.co.uk.
Sofie F M BhattiDepartment of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, 9820, Belgium. sofie.bhatti@ugent.be.
Akos PakozdyClinical Unit of Internal Medicine Small Animals, University of Veterinary Medicine, Veterinärplatz 1, 1210, Vienna, Austria. akos.pakozdy@vetmeduni.ac.at.
Edward E PattersonUniversity of Minnesota College of Veterinary Medicine, D426 Veterinary Medical Center, 1352 Boyd Avenue, St. Paul, MN, 55108, USA. patte037@umn.edu.
Simon PlattCollege of Veterinary Medicine, University of Georgia, 501 DW Brooks Drive, Athens, GA, 30602, USA. srplatt@uga.edu.
Rowena M A PackerDepartment of Clinical Science and Services, Royal Veterinary College, Hatfield, AL9 7TA, Hertfordshire, UK. rpacker@rvc.ac.uk.
Holger A VolkDepartment of Clinical Science and Services, Royal Veterinary College, Hatfield, AL9 7TA, Hertfordshire, UK. hvolk@rvc.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine idiopathic epilepsy is a common neurological disease affecting both purebred and crossbred dogs. Various breed-specific cohort, epidemiological and genetic studies have been conducted to date, which all improved our knowledge and general understanding of canine idiopathic epilepsy, and in particular our knowledge of those breeds studied. However, these studies also frequently revealed differences between the investigated breeds with respect to clinical features, inheritance and prevalence rates. Awareness and observation of breed-specific differences is important for successful management of the dog with epilepsy in everyday clinical practice and furthermore may promote canine epilepsy research. The following manuscript reviews the evidence available for breeds which have been identified as being predisposed to idiopathic epilepsy with a proven or suspected genetic background, and highlights different breed specific clinical features (e.g. age at onset, sex, seizure type), treatment response, prevalence rates and proposed inheritance reported in the literature. In addition, certain breed-specific diseases that may act as potential differentials for idiopathic epilepsy are highlighted.

Indexed as

Genetic Predisposition to DiseaseInternationalityAgingAnimalsBreedingDog DiseasesDogsEpilepsyFemaleMaleSex FactorsVeterinary Medicine

Identifiers

PMID26316206
PMCPMC4552344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.