ArticleWorld journal of surgery2016
Augmented Reality Guidance for the Resection of Missing Colorectal Liver Metastases: An Initial Experience.
Article in World journal of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- A Review of Cognitive Support Systems in the Operating Room.Surgical innovation · 2024Pooled it
- Applicability of augmented reality in orthopedic surgery - A systematic review.BMC musculoskeletal disorders · 2020Pooled it
- Augmented reality in open surgery.Updates in surgery · 2018Pooled it
- From Prototype to Practice: Mixed Methods Study of Human-Centered Design and Usability Evaluation of Augmented Reality for Complex Oncology Surgical Workflows.JMIR human factors · 2026Article
- The impact of 3-dimensional models and surgical navigation for open liver surgery.International journal of computer assisted radiology and surgery · 2025Article
- Artificial Intelligence and Digital Tools Across the Hepato-Pancreato-Biliary Surgical Pathway: A Systematic Review.Journal of clinical medicine · 2025Review
- Artificial intelligence in hepatopancreatobiliary surgery for clinical outcome prediction: current perspective and future direction.Journal of robotic surgery · 2025Review
- Leveraging augmented reality for dynamic guidance in 3-dimensional laparoscopic and robotic liver surgery: a prospective case series study.Annals of surgical treatment and research · 2025Article
- Augmented and mixed reality in liver surgery: a comprehensive narrative review of novel clinical implications on cohort studies.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Article
- Mixed reality applications in upper extremity surgery: the future is now.EFORT open reviews · 2024Review
- Smart Operating Room in Digestive Surgery: A Narrative Review.Healthcare (Basel, Switzerland) · 2024Review
- Minimally invasive and invasive liver surgery based on augmented reality training: a review of the literature.Journal of robotic surgery · 2023Review
- Laparoscopic liver resection with "ultrasonic scalpel mimic CUSA" technique.Surgical endoscopy · 2022Article
- Augmented reality in laparoscopic liver resection evaluated on an ex-vivo animal model with pseudo-tumours.Surgical endoscopy · 2022Article
- Research on registration and navigation technology of augmented reality for ex-vivo hepatectomy.International journal of computer assisted radiology and surgery · 2022Article
- Artificial Intelligence in hepatology, liver surgery and transplantation: Emerging applications and frontiers of research.World journal of hepatology · 2021Review
- Review
- Augmented Reality during Open Liver Surgery Using a Markerless Non-rigid Registration System.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Role of artificial intelligence in hepatobiliary and pancreatic surgery.World journal of gastrointestinal surgery · 2021Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundModern chemotherapy achieves the shrinking of colorectal cancer liver metastases (CRLM) to such extent that they may disappear from radiological imaging. Disappearing CRLM rarely represents a complete pathological remission and have an important risk of recurrence. Augmented reality (AR) consists in the fusion of real-time patient images with a computer-generated 3D virtual patient model created from pre-operative medical imaging. The aim of this prospective pilot study is to investigate the potential of AR navigation as a tool to help locate and surgically resect missing CRLM.
methodsA 3D virtual anatomical model was created from thoracoabdominal CT-scans using customary software (VR RENDER(®), IRCAD). The virtual model was superimposed to the operative field using an Exoscope (VITOM(®), Karl Storz, Tüttlingen, Germany). Virtual and real images were manually registered in real-time using a video mixer, based on external anatomical landmarks with an estimated accuracy of 5 mm. This modality was tested in three patients, with four missing CRLM that had sizes from 12 to 24 mm, undergoing laparotomy after receiving pre-operative oxaliplatin-based chemotherapy.
resultsAR display and fine registration was performed within 6 min. AR helped detect all four missing CRLM, and guided their resection. In all cases the planned security margin of 1 cm was clear and resections were confirmed to be R0 by pathology. There was no postoperative major morbidity or mortality. No local recurrence occurred in the follow-up period of 6-22 months.
conclusionsThis initial experience suggests that AR may be a helpful navigation tool for the resection of missing CRLM.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.