ArticleThe ISME journal2016
Temporal variation selects for diet-microbe co-metabolic traits in the gut of Gorilla spp.
Article in The ISME journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed, 105 citations in OpenAlex.
- The Importance of Sociality and Diet in Explaining Variation in the Bonobo Gut Microbiota.American journal of primatology · 2026Article
- Timing Is Everything: The Effect of Exposure to Pollution on Wildlife Gut Microbiota Is Contingent on Season.Molecular ecology · 2026Article
- Gut microbiome profiles of two limestone forest-dwelling langurs show stronger influence of host-associated factors than environment.Frontiers in microbiology · 2026Article
- Adaptive Evolution in the Mammalian Gut Microbiota: Insights and Discoveries.Current microbiology · 2025Review
- Seasonal Adaptation of the Gut Microbiome in Japanese Macaques: Linking Gut Microbiome Shifts With Fermentative Function.Ecology and evolution · 2025Article
- Gut fungal profiles reveal phylosymbiosis and codiversification across humans and nonhuman primates.PLoS biology · 2025Article
- Climate, diet, and nutrition drive gut microbiome variation in a fruit-specialist primate.Scientific reports · 2025Article
- Cardiometabolic disease risk in gorillas is associated with altered gut microbial metabolism.NPJ biofilms and microbiomes · 2025Article
- Comparative study of gut microbiota reveals the adaptive strategies of gibbons living in suboptimal habitats.NPJ biofilms and microbiomes · 2025Article
- Gut microbiota profiles of sympatric snub-nosed monkeys and macaques in Qinghai-Tibetan Plateau show influence of phylogeny over diet.Communications biology · 2025Article
- Temporal patterns of gut microbiota in lemurs (Eulemur rubriventer) living in intact and disturbed habitats in a novel sample type.American journal of primatology · 2025Article
- Global meta-analysis reveals the drivers of gut microbiome variation across vertebrates.iMetaOmics · 2024Article
- Maintaining the native gut microbiota of bharal (Frontiers in microbiology · 2024Article
- Seasonal dietary shifts alter the gut microbiota of a frugivorous lizardEcology and evolution · 2023Article
- Gut microbiome responds compositionally and functionally to the seasonal diet variations in wild gibbons.NPJ biofilms and microbiomes · 2023Article
- Metagenome and metabolome insights into the energy compensation and exogenous toxin degradation of gut microbiota in high-altitude rhesus macaques (Macaca mulatta).NPJ biofilms and microbiomes · 2023Article
- Gut microbiota variation between climatic zones and due to migration strategy in passerine birds.Frontiers in microbiology · 2023Article
- Individuality and stability of the koala (PeerJ · 2023Article
- The History of the Intestinal Microbiota and the Gut-Brain Axis.Pathogens (Basel, Switzerland) · 2022Review
- Seasonal responses and host uniqueness of gut microbiome of Japanese macaques in lowland Yakushima.Animal microbiome · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
16 authors at 9 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the critical role that our gastrointestinal microbes play in host physiology is now well established, we know little about the factors that influenced the evolution of primate gut microbiomes. To further understand current gut microbiome configurations and diet-microbe co-metabolic fingerprints in primates, from an evolutionary perspective, we characterized fecal bacterial communities and metabolomic profiles in 228 fecal samples of lowland and mountain gorillas (G. g. gorilla and G. b. beringei, respectively), our closest evolutionary relatives after chimpanzees. Our results demonstrate that the gut microbiomes and metabolomes of these two species exhibit significantly different patterns. This is supported by increased abundance of metabolites and bacterial taxa associated with fiber metabolism in mountain gorillas, and enrichment of markers associated with simple sugar, lipid and sterol turnover in the lowland species. However, longitudinal sampling shows that both species' microbiomes and metabolomes converge when hosts face similar dietary constraints, associated with low fruit availability in their habitats. By showing differences and convergence of diet-microbe co-metabolic fingerprints in two geographically isolated primate species, under specific dietary stimuli, we suggest that dietary constraints triggered during their adaptive radiation were potential factors behind the species-specific microbiome patterns observed in primates today.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.