Evidence map›Paper›PMID 26315949›Full record

ArticleBMC public health2015

The RESPECT study: RESearch on the PrEvalence and the diagnosis of COPD and its Tobacco-related etiology: a study protocol.

Elena Andreeva, Marina Pokhaznikova, Anatoly Lebedev, Irina Moiseeva, Anton Kozlov, Olga Kuznetsova, Jean-Marie Degryse

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02307799 (A RESearch on the PrEvalence and the Diagnosis of COPD and Its Tobacco-related Etiology), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02307799 completednot on this map

A RESearch on the PrEvalence and the Diagnosis of COPD and Its Tobacco-related Etiology (RESPECT)

TypeobservationalSponsorUniversité Catholique de LouvainRan2012 to 2019Enrolled3,133ConditionsChronic Obstructive Pulmonary Disease
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Elena AndreevaInstitute of Health and Society, Université Catholique de Louvain, IRSS, Clos Chapelle-aux-Champs, 30/10.15, 1200, Brussels, Belgium. elena.andreeva@student.uclouvain.be.
Marina PokhaznikovaDepartment of Family Medicine, North-West State Medical University (named after I.I. Mechnikov), Saint Petersburg, the Russian Federation. pokmar@mail.ru.
Anatoly LebedevDepartment of Family Medicine, North-West State Medical University (named after I.I. Mechnikov), Saint Petersburg, the Russian Federation. lebedev_ak@mail.ru.
Irina MoiseevaDepartment of Family Medicine, North-West State Medical University (named after I.I. Mechnikov), Saint Petersburg, the Russian Federation. dr-moiseeva@yandex.ru.
Anton KozlovDepartment of Family Medicine, North-West State Medical University (named after I.I. Mechnikov), Saint Petersburg, the Russian Federation. Anton.Kozlov@szgmu.ru.
Olga KuznetsovaDepartment of Family Medicine, North-West State Medical University (named after I.I. Mechnikov), Saint Petersburg, the Russian Federation. oukuznetsova@mail.ru.
Jean-Marie DegryseInstitute of Health and Society, Université Catholique de Louvain, IRSS, Clos Chapelle-aux-Champs, 30/10.15, 1200, Brussels, Belgium. jean-marie.degryse@uclouvain.be.
North-Western State Medical University named after I.I. Mechnikov · RUNorthern State Medical University · RUUCLouvain · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmoking remains a leading health risk factor among Europeans. Tobacco, together with other factors, will lead to an expansive epidemic of chronic diseases, including COPD, among the working population in Russia. The general aim of the RESearch on the PrEvalence and the diagnosis of COPD and its Tobacco-related etiology (RESPECT) study is to gain a better understanding of the prevalence, pathogenesis and symptoms of COPD. METHODS/

designThe RESPECT study is a prospective, population-based cohort study of subjects aged 35-70 years in two north-west regions of the Russian Federation (Saint Petersburg and Arkhangelsk). The study includes three components: a cross-sectional study (prevalence), a case-control study and a cohort study (diagnostic). An investigator who interviewed the patient completed three questionnaires. Spirometry, including a reversibility test, was offered to all participants. Individuals displaying forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) < 0.7 and/or FEV1/FVC < the lower limit of normal before and/or after bronchodilation were included in a follow-up study and were examined by a pulmonologist using a standardized comprehensive examination protocol. A future case-control study of two matched groups of patients (heavy smokers with COPD versus heavy smokers without COPD) will provide information on which factors (biomarkers, including pneumoproteins, in serum and induced sputum) are related to tobacco-induced COPD. DISCUSSION: In total, 3133 individuals (2122 from St. Petersburg and 1012 from Arkhangelsk) aged 35-70 years agreed to participate in this study and met the inclusion criteria. In total, 2974 participants met the quality criteria for spirometry, and 2388 reversibility tests were performed. A cohort of newly defined obstructive pulmonary disease patients (247 persons) was established for follow-up investigation. The RESPECT study will provide information regarding the prevalence of COPD in the north-west region of the Russian Federation. Moreover, the comprehensive RESPECT database will enable us to explore new research questions, provide novel insight into the risk factors and different phenotypes of COPD, and contribute to an improved understanding of the reasons why some heavy smokers develop the disease whereas others do not. CLINICAL

trial registrationNCT02307799 (the release date: 12/01/2014).

Indexed as

Research DesignAdultAgedCase-Control StudiesChronic DiseaseCross-Sectional StudiesFollow-Up StudiesForced Expiratory VolumeHumansMaleMiddle AgedPrevalenceProspective StudiesPulmonary Disease, Chronic ObstructiveResearchRisk Factors

Identifiers

PMID26315949
PMCPMC4552306
OpenAlexW2147300439

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.