Evidence map›Paper›PMID 26315891›Full record

ArticleScientific reports2015

Enhancing Tabletop X-Ray Phase Contrast Imaging with Nano-Fabrication.

Houxun Miao, Andrew A Gomella, Katherine J Harmon, Eric E Bennett, Nicholas Chedid, Sami Znati, Alireza Panna, Barbara A Foster, Priya Bhandarkar, Han Wen

Abstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Edge-illumination x-ray phase-contrast imaging.Journal of physics. Condensed matter : an Institute of Physics journal · 2021
    Review
  4. Dual Energy Differential Phase Contrast CT (DE-DPC-CT) Imaging.IEEE transactions on medical imaging · 2020
    Article
  5. Article
  6. Article
  7. Impact of the sensitivity factor on the signal-to-noise ratio in grating-based phase contrast imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Cryogenic Etching of High Aspect Ratio 400 nm Pitch Silicon Gratings.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2016
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Houxun MiaoImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Andrew A GomellaImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Katherine J HarmonImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Eric E BennettImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Nicholas ChedidImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Sami ZnatiImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Alireza PannaImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Barbara A FosterBreast Imaging Center, Walter Reed National Military Medical Center, Bethesda, MD 20889.
Priya BhandarkarBreast Imaging Center, Walter Reed National Military Medical Center, Bethesda, MD 20889.
Han WenImaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.

Funding

NHLBI Animal Program DivisionZIGHL006020 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CLARK, TANNIA · 2009 to 2025
$47.3M
X-Ray Phase Contrast Imaging Concepts and SystemsZIAHL004606 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI WEN, HAN · 2009 to 2022
$10.1M
6 · The paper itself

Abstract

X-ray phase-contrast imaging is a promising approach for improving soft-tissue contrast and lowering radiation dose in biomedical applications. While current tabletop imaging systems adapt to common x-ray tubes and large-area detectors by employing absorptive elements such as absorption gratings or monolithic crystals to filter the beam, we developed nanometric phase gratings which enable tabletop x-ray far-field interferometry with only phase-shifting elements, leading to a substantial enhancement in the performance of phase contrast imaging. In a general sense the method transfers the demands on the spatial coherence of the x-ray source and the detector resolution to the feature size of x-ray phase masks. We demonstrate its capabilities in hard x-ray imaging experiments at a fraction of clinical dose levels and present comparisons with the existing Talbot-Lau interferometer and with conventional digital radiography.

Identifiers

PMID26315891
PMCPMC4551996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.