Evidence map›Paper›PMID 26315787›Full record

ArticleBMC public health2015

Determinants of hypertension in a young adult Ugandan population in epidemiological transition-the MEPI-CVD survey.

James Kayima, Joaniter Nankabirwa, Isaac Sinabulya, Jane Nakibuuka, Xiaofeng Zhu, Mahboob Rahman, Christopher T Longenecker, Achilles Katamba, Harriet Mayanja-Kizza, Moses R Kamya

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Association between HIV and Prevalent Hypertension and Diabetes Mellitus in South Africa: Analysis of a Nationally Representative Cross-Sectional Survey.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Availability, functionality and access of blood pressure machines at the points of care in public primary care facilities in Tororo district, Uganda.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2021
    Article
  18. Prevalence and Risk Factors of Hypertension Among Young Adults in Albania.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

James KayimaDepartment of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda. jkkayima@gmail.com.
Joaniter NankabirwaClinical Epidemiology Unit, Makerere University College of Health Sciences, Kampala, Uganda. jnankabirwa@yahoo.co.uk.
Isaac SinabulyaDepartment of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda. ssinabulyaisaac@gmail.com.
Jane NakibuukaDepartment of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda. nakibuukajm@yahoo.com.
Xiaofeng ZhuDepartment of Epidemiology, Case Western Reserve University School of Medicine Cleveland, Cleveland, OH, USA. xiaofeng.zhu@case.edu.
Mahboob RahmanClinical Hypertension Program, University Hospitals Case Medical Center, Cleveland, OH, USA. Mahboob.Rahman@uhhospitals.org.
Christopher T LongeneckerHarrington Heart and Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, USA. Chris.Longenecker@uhhospitals.org.
Achilles KatambaClinical Epidemiology Unit, Makerere University College of Health Sciences, Kampala, Uganda. akatamba@yahoo.com.
Harriet Mayanja-KizzaDepartment of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda. hmk@chs.mak.ac.ug.
Moses R KamyaDepartment of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda. mkamya@infocom.co.ug.
Makerere University · UGUniversity Hospitals Case Medical Center · USCase Western Reserve University · US

Funding

Linked; Building Capacity for Cardiovascular Research and Training in UgandaR24TW008861 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2010 to 2014
$2.5M
Pericardial fat, inflammation, and structural heart disease in HIVK23HL123341 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI LONGENECKER, CHRIS TODD · 2014 to 2018
$885k
FIC NIH HHS R24 TW008861NHLBI NIH HHS K23 HL123341
6 · The paper itself

Abstract

backgroundHigh blood pressure is the principal risk factor for stroke, heart failure and kidney failure in the young population in Africa. Control of hypertension is associated with a larger reduction in morbidity and mortality in younger populations compared with the elderly; however, blood pressure control efforts in the young are hampered by scarcity of data on prevalence and factors influencing awareness, treatment and control of hypertension. We aimed to describe the prevalence of prehypertension and hypertension among young adults in a peri-urban district of Uganda and the factors associated with occurrence of hypertension in this population.

methodsThis cross-sectional study was conducted between August, 2012 and May 2013 in Wakiso district, a suburban district that that encircles Kampala, Uganda's capital city. We collected data on socio-demographic characteristics and hypertension status using a modified STEPs questionnaire from 3685 subjects aged 18-40 years selected by multistage cluster sampling. Blood pressure and anthropometric measurements were performed using standardized protocols. Fasting blood sugar and HIV status were determined using a venous blood sample. Association between hypertension status and various biosocial factors was assessed using logistic regression.

resultsThe overall prevalence of hypertension was 15% (95% CI 14.2 - 19.6) and 40% were pre-hypertensive. Among the 553 hypertensive participants, 76 (13.7%) were aware of their diagnosis and all these participants had initiated therapy with target blood pressure control attained in 20% of treated subjects. Hypertension was significantly associated with the older age-group, male sex and obesity. There was a significantly lower prevalence of hypertension among participants with HIV OR 0.6 (95% CI 0.4-0.8, P = 0.007).

conclusionThere is a high prevalence of high blood pressure in this young periurban population of Uganda with sub-optimal diagnosis and control. There is previously undocumented high rate of treatment, a unique finding that may be exploited to drive efforts to control hypertension. Specific programs for early diagnosis and treatment of hypertension among the young should be developed to improve control of hypertension. The relationship between HIV infection and blood pressure requires further clarification by longitudinal studies.

Indexed as

AdolescentAdultAfricaBlood PressureBody Weights and MeasuresComorbidityCross-Sectional StudiesFemaleHIV InfectionsHumansHypertensionLogistic ModelsLongitudinal StudiesMalePrehypertensionPrevalence

Identifiers

PMID26315787
PMCPMC4552375
OpenAlexW2098703247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.