Evidence map›Paper›PMID 26315636›Full record

ReviewAnesthesiology clinics2015

Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly.

Miles Berger, Jacob W Nadler, Jeffrey Browndyke, Niccolo Terrando, Vikram Ponnusamy, Harvey Jay Cohen, Heather E Whitson, Joseph P Mathew

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Anesthesiology clinics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  10. Spinal Dexamethasone Effect on Cognitive Disorders After Hip Surgery.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2023
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miles BergerDepartment of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA. Electronic address: miles.berger@duke.edu.
Jacob W NadlerDepartment of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.
Jeffrey BrowndykeDepartment of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.
Niccolo TerrandoDepartment of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.
Vikram PonnusamyDepartment of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.
Harvey Jay CohenDepartment of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.
Heather E WhitsonDepartment of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.
Joseph P MathewDepartment of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Sarah B. Peskoe · 2006 to 2026
$24.6M
INTEGRATED TRAINING IN ANESTHESIOLOGY RESEARCHT32GM008600 · NIGMS · DUKE UNIVERSITY · PI Miriam Treggiari · 1996 to 2026
$6.6M
Lifestyle, CVD Risk and Cognitive ImpairmentR01HL109219 · NHLBI · DUKE UNIVERSITY · PI BLUMENTHAL, JAMES A · 2011 to 2015
$4.1M
Advancing Geriatrics Infrastructure & Network Growth - Admin Supplement: Designing and Testing an Informatics Tool to Aid Prescribers in Reducing Anticholinergic Burden in Older AdultsR24AG045050 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GURWITZ, JERRY H · 2014 to 2017
$3.6M
Cognitive Changes and Brain Connectivity in Age-Related Macular DegenerationR01AG043438 · NIA · DUKE UNIVERSITY · PI WHITSON, HEATHER E. · 2013 to 2017
$2.1M
Lidocaine for Neuroprotection During Cardiac SurgeryR01HL096978 · NHLBI · DUKE UNIVERSITY · PI MATHEW, JOSEPH P · 2009 to 2013
$1.8M
Assessing Large-scale Brain Connectivities in Mild Cognitive ImpairmentR01AG042599 · NIA · UNIVERSITY OF GEORGIA · PI LIU, TIANMING · 2013 to 2017
$1.4M
Cortical Beta-amyloid Levels and Neurocognitive Performance After Cardiac SurgeryR21HL108280 · NHLBI · DUKE UNIVERSITY · PI MATHEW, JOSEPH P · 2011 to 2012
$432k
Functional Connectivity Changes In Attention Networks after Cardiac SurgeryR21HL109971 · NHLBI · DUKE UNIVERSITY · PI BROWNDYKE, JEFFREY N, MATHEW, JOSEPH P · 2012 to 2013
$422k
NHLBI NIH HHS HL096978NHLBI NIH HHS HL108280NHLBI NIH HHS HL109971NHLBI NIH HHS R01-HL109219NHLBI NIH HHS R21-HL109971NIA NIH HHS P30 AG028716NIA NIH HHS P30AG028716NIA NIH HHS R01-AG042599NIA NIH HHS R01 AG043438NIA NIH HHS R01AG043438NIA NIH HHS R24 AG045050NIA NIH HHS R24AG045050NIGMS NIH HHS T32 GM008600
6 · The paper itself

Abstract

Postoperative cognitive dysfunction (POCD) is a common complication associated with significant morbidity and mortality in elderly patients. There is much interest in and controversy about POCD, reflected partly in the increasing number of articles published on POCD recently. Recent work suggests surgery may also be associated with cognitive improvement in some patients, termed postoperative cognitive improvement (POCI). As the number of surgeries performed worldwide approaches 250 million per year, optimizing postoperative cognitive function and preventing/treating POCD are major public health issues. In this article, we review the literature on POCD and POCI, and discuss current research challenges in this area.

Indexed as

AgedAged, 80 and overCognition DisordersDeliriumHumansPostoperative ComplicationsQuality of LifeResilience, PsychologicalAnesthesiaElderlyPost-operative cognitive declinePost-operative cognitive dysfunctionPost-operative cognitive improvementSurgery

Identifiers

PMID26315636
PMCPMC4555995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.