Evidence map›Paper›PMID 26315630›Full record

ReviewAnesthesiology clinics2015

Physiology Considerations in Geriatric Patients.

Bret D Alvis, Christopher G Hughes

Open access · greenAbstract readReview
In one paragraph

Review in Anesthesiology clinics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 190 citations in OpenAlex.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bret D AlvisDivision of Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, 1211 21st Avenue South, 526 MAB, Nashville, TN 37212, USA.
Christopher G HughesDivision of Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, 1211 21st Avenue South, 526 MAB, Nashville, TN 37212, USA. Electronic address: christopher.hughes@vanderbilt.edu.
Vanderbilt University · US

Funding

Altering Sedation Paradigms to Improve Brain Injury and Survival in Severe SepsisR01HL111111 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PANDHARIPANDE, PRATIK · 2012 to 2017
$3.7M
Role of Endothelial and Brain Injury in Acute and Long-term Brain DysfunctionR03AG045085 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HUGHES, CHRISTOPHER · 2014 to 2015
$232k
NHLBI NIH HHS HL111111NHLBI NIH HHS R01 HL111111NIA NIH HHS R03 AG045085NIA NIH HHS R03AG045085
6 · The paper itself

Abstract

Physiology changes at the structural, functional, and molecular levels as people age, and every major organ system experiences physiologic change with time. The changes to the nervous system result mostly in cognitive impairments, the cardiovascular system develops higher blood pressures with lower cardiac output, the respiratory system undergoes a reduction of arterial oxyhemoglobin levels, the gastrointestinal system experiences delayed gastric emptying and reduction of hepatic metabolism, and the renal system experiences a diminished glomerular filtration rate. Combined, these changes create a complex physiologic condition. This unique physiology must be taken into consideration for geriatric patients undergoing general anesthesia.

Indexed as

AgedAged, 80 and overAgingGastrointestinal TractGeriatricsHemodynamicsHumansKidneyPatientsRespiratory SystemAgingCardiovascular agingGeriatricNeurologic agingPhysiology

Identifiers

PMID26315630
PMCPMC4556136
OpenAlexW2140485502

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.