Evidence map›Paper›PMID 26315600›Full record

ReviewExperimental & molecular medicine2015

Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control.

Prasannavenkatesh Durai, Maria Batool, Masaud Shah, Sangdun Choi

Open access · goldAbstract readReview
In one paragraph

Review in Experimental & molecular medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 128 citations in OpenAlex.

  1. Article
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  11. Toll-like Receptor Mediation in SARS-CoV-2: A Therapeutic Approach.International journal of molecular sciences · 2022
    Review
  12. Review
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  16. Review
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Prasannavenkatesh DuraiDepartment of Molecular Science and Technology, Ajou University, Suwon, Korea.
Maria BatoolDepartment of Molecular Science and Technology, Ajou University, Suwon, Korea.
Masaud ShahDepartment of Molecular Science and Technology, Ajou University, Suwon, Korea.
Sangdun ChoiDepartment of Molecular Science and Technology, Ajou University, Suwon, Korea.
Ajou University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) causes high fever, cough, acute respiratory tract infection and multiorgan dysfunction that may eventually lead to the death of the infected individuals. MERS-CoV is thought to be transmitted to humans through dromedary camels. The occurrence of the virus was first reported in the Middle East and it subsequently spread to several parts of the world. Since 2012, about 1368 infections, including ~487 deaths, have been reported worldwide. Notably, the recent human-to-human 'superspreading' of MERS-CoV in hospitals in South Korea has raised a major global health concern. The fatality rate in MERS-CoV infection is four times higher compared with that of the closely related severe acute respiratory syndrome coronavirus infection. Currently, no drug has been clinically approved to control MERS-CoV infection. In this study, we highlight the potential drug targets that can be used to develop anti-MERS-CoV therapeutics.

Indexed as

AnimalsAntiviral AgentsCell LineCoronavirus InfectionsDipeptidyl Peptidase 4Disease OutbreaksDrug DiscoveryHost-Pathogen InteractionsHumansMiddle East Respiratory Syndrome CoronavirusMolecular Targeted TherapySpike Glycoprotein, CoronavirusAntiviral AgentsDipeptidyl Peptidase 4Spike Glycoprotein, Coronavirus

Identifiers

PMID26315600
PMCPMC4558490
OpenAlexW1151195487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.