Evidence map›Paper›PMID 26315536›Full record

SynthesisPsychological medicine2016

Preventing depression and anxiety in young people: a review of the joint efficacy of universal, selective and indicated prevention.

E A Stockings, L Degenhardt, T Dobbins, Y Y Lee, H E Erskine, H A Whiteford, G Patton

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Psychological medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed, 16 pooled it
25.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 16 syntheses or guidelines pooled it, 346 citations in OpenAlex.

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82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

E A StockingsNational Drug and Alcohol Research Centre (NDARC),University of New South Wales (UNSW),Randwick,New South Wales,Australia.
L DegenhardtNational Drug and Alcohol Research Centre (NDARC),University of New South Wales (UNSW),Randwick,New South Wales,Australia.
T DobbinsNational Drug and Alcohol Research Centre (NDARC),University of New South Wales (UNSW),Randwick,New South Wales,Australia.
Y Y LeeQueensland Centre for Mental Health Research (QCMHR),The Park Centre for Mental Health,Wacol,Queensland,Australia.
H E ErskineInstitute for Health Metrics and Evaluation (IHME),University of Washington,Seattle,Washington,USA.
H A WhitefordInstitute for Health Metrics and Evaluation (IHME),University of Washington,Seattle,Washington,USA.
G PattonCentre for Adolescent Health,Murdoch Children's Research Institute (MCRI),Royal Children's Hospital,Parkville,Victoria,Australia.
Queensland Centre for Mental Health Research · AUAustralian National University · AUInstitute for Health Metrics and Evaluation · USMurdoch Children's Research Institute · AUUniversity of Washington · USUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression and anxiety (internalizing disorders) are the largest contributors to the non-fatal health burden among young people. This is the first meta-analysis to examine the joint efficacy of universal, selective, and indicated preventive interventions upon both depression and anxiety among children and adolescents (5-18 years) while accounting for their co-morbidity. We conducted a systematic review of reviews in Medline, PsycINFO and the Cochrane Library of Systematic Reviews, from 1980 to August 2014. Multivariate meta-analysis examined the efficacy of preventive interventions on depression and anxiety outcomes separately, and the joint efficacy on both disorders combined. Meta-regressions examined heterogeneity of effect according to a range of study variables. Outcomes were relative risks (RR) for disorder, and standardized mean differences (Cohen's d) for symptoms. One hundred and forty-six randomized controlled trials (46 072 participants) evaluated universal (children with no identified risk, n = 54) selective (population subgroups of children who have an increased risk of developing internalizing disorders due to shared risk factors, n = 45) and indicated prevention (children with minimal but detectable symptoms of an internalizing disorder, n = 47), mostly using psychological-only strategies (n = 105). Reductions in internalizing disorder onset occurred up to 9 months post-intervention, whether universal [RR 0.47, 95% confidence interval (CI) 0.37-0.60], selective (RR 0.61, 95% CI 0.43-0.85) or indicated (RR 0.48, 95% CI 0.29-0.78). Reductions in internalizing symptoms occurred up to 12 months post-intervention for universal prevention; however, reductions only occurred in the shorter term for selective and indicated prevention. Universal, selective and indicated prevention interventions are efficacious in reducing internalizing disorders and symptoms in the short term. They might be considered as repeated exposures in school settings across childhood and adolescence. (PROSPERO registration: CRD42014013990.).

Indexed as

Outcome Assessment, Health CareAdolescentAnxiety DisordersChildChild, PreschoolDepressive DisorderEarly Medical InterventionHumansanxietychild and adolescentDepressionearly interventionpreventionschool

Identifiers

PMID26315536
OpenAlexW1864246873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.