Evidence map›Paper›PMID 26315321›Full record

ArticleJournal of the American Medical Directors Association2015

Brain health: the importance of recognizing cognitive impairment: an IAGG consensus conference.

John E Morley, John C Morris, Marla Berg-Weger, Soo Borson, Brian D Carpenter, Natalia Del Campo, Bruno Dubois, Keith Fargo, L Jaime Fitten, Joseph H Flaherty and 13 more

Registry-linked trialOpen access · bronzeAbstract readConsensus Statement
In one paragraph

Article in Journal of the American Medical Directors Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04440969 (Dementia - Early Detection and Intervention), which is not on this map. Cited by 122 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 6 pooled it
21.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04440969 nacompletednot on this mapstarted 2018, after this paper: background citation

Dementia - Early Detection and Intervention

TypeinterventionalSponsorGeriatric Education and Research InstituteRan2018 to 2020Enrolled199ConditionsCognitive Decline, Cognitive Impairment, MildArmsMulti-domain intervention
3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 6 syntheses or guidelines pooled it, 317 citations in OpenAlex.

  1. Pooled it
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  7. Trial
  8. Mixture of organic pollutants is associated with cognitive aging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Trial
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  10. Review
  11. Article
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  15. Cognitive Impairments and Health System Outcomes in Inpatient Rehabilitation: A Comparison of Patients With Stroke and Those With Type II Diabetes Mellitus.The American journal of occupational therapy : official publication of the American Occupational Therapy Association · 2026
    Observational
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 14 institutions in 7 countries.

John E MorleyDivisions of Geriatric Medicine and Endocrinology, Saint Louis University School of Medicine, St Louis, MO. Electronic address: morley@slu.edu.
John C MorrisKnight Alzheimer Disease Research Center, Washington University School of Medicine, St Louis, MO.
Marla Berg-WegerDivision of Geriatric Medicine, School of Social Work, Saint Louis University, St Louis, MO.
Soo BorsonDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA.
Brian D CarpenterKnight Alzheimer Disease Research Center, Washington University School of Medicine, St Louis, MO.
Natalia Del CampoInstitute of Aging, University Hospital of Toulouse, Toulouse, France.
Bruno DuboisDepartment of Neurology, Université Pierreet Marie Curie, Salpetriere Hospital, Paris, France.
Keith FargoScientific Programs and Outreach, Alzheimer's Association, Chicago, IL.
L Jaime FittenPsychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA and Geriatric Psychiatry, Greater Los Angeles VA, Sepulveda Campus, Los Angeles, CA.
Joseph H FlahertyDivision of Geriatric Medicine, Saint Louis University School of Medicine, St Louis, MO.
Mary GanguliDepartments of Psychiatry, Neurology and Epidemiology, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, PA.
George T GrossbergDepartment of Neurology and Psychiatry, Geriatric Psychiatry, Saint Louis University School of Medicine, St Louis, MO.
Theodore K MalmstromDepartment of Neurology and Psychiatry, Saint Louis University School of Medicine, St Louis, MO.
Ronald D PetersenDepartment of Neurology, Mayo Clinic College of Medicine, Rochester, MN.
Carroll RodriguezPublic Policy and Communications, Alzheimer's Association, St Louis, MO.
Andrew J SaykinDepartment of Radiology and Imaging Sciences and the Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN.
Philip ScheltensVU University Medical Center, Alzheimer Center, Amsterdam, The Netherlands.
Eric G TangalosDepartment of Medicine, Mayo Clinic, Rochester, MN.
Joe VergheseDivision of Geriatrics, Albert Einstein College of Medicine, Bronx, NY.
Gordon WilcockNuffield Department of Clinical Medicine, Oxford Institute of Population Ageing, Oxford, United Kingdom.
Bengt WinbladDivision for Neurogeriatrics, Care Sciences and Society, Department of NVS, Center for Alzheimer Research, Karolinska Institutet, Huddinge, Sweden.
Jean WooDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
Bruno VellasDepartment of Geriatrics, CHU Toulouse, Toulouse, France.
Saint Louis University · USAlzheimer's Association · USAlbert Einstein College of Medicine · USAmsterdam UMC Location Vrije Universiteit Amsterdam · NLChinese University of Hong Kong · HKIndiana University – Purdue University Indianapolis · USInstitut de Mathématiques de Toulouse · FRKarolinska Institutet · SEMayo Clinic · USMayo Clinic in Arizona · USOxford Fertility · GBUCLouvain Saint-Louis Brussels · BEUniversity of Pittsburgh · USUniversity of Washington · US

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
Memory Circuitry in MCI and Early Alzheimer’s Disease Prodrome: Molecular DriversR01AG019771 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 2001 to 2021
$6.9M
NIA NIH HHS P30 AG010133NIA NIH HHS R01 AG019771PHS HHS U1QHP28716
6 · The paper itself

Abstract

Cognitive impairment creates significant challenges for patients, their families and friends, and clinicians who provide their health care. Early recognition allows for diagnosis and appropriate treatment, education, psychosocial support, and engagement in shared decision-making regarding life planning, health care, involvement in research, and financial matters. An IAGG-GARN consensus panel examined the importance of early recognition of impaired cognitive health. Their major conclusion was that case-finding by physicians and health professionals is an important step toward enhancing brain health for aging populations throughout the world. This conclusion is in keeping with the position of the United States' Centers for Medicare and Medicaid Services that reimburses for detection of cognitive impairment as part the of Medicare Annual Wellness Visit and with the international call for early detection of cognitive impairment as a patient's right. The panel agreed on the following specific findings: (1) validated screening tests are available that take 3 to 7 minutes to administer; (2) a combination of patient- and informant-based screens is the most appropriate approach for identifying early cognitive impairment; (3) early cognitive impairment may have treatable components; and (4) emerging data support a combination of medical and lifestyle interventions as a potential way to delay or reduce cognitive decline.

Indexed as

Mass ScreeningAgedCognition DisordersDecision MakingEarly DiagnosisHumansAlzheimer diseasecase findingcognitive frailtyCognitive impairmentMCI

Identifiers

PMID26315321
PMCPMC4822500
OpenAlexW2133114348

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.