Evidence map›Paper›PMID 26314736›Full record

ArticleGlycoconjugate journal2016

GlycoMob: an ion mobility-mass spectrometry collision cross section database for glycomics.

Weston B Struwe, Kevin Pagel, Justin L P Benesch, David J Harvey, Matthew P Campbell

Abstract read
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Article in Glycoconjugate journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Labeling of Mucin-TypeACS measurement science au · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Measuring change in glycoprotein structure.Current opinion in structural biology · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. State-of-the-Art Glycomics Technologies in Glycobiotechnology.Advances in biochemical engineering/biotechnology · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weston B StruweDepartment of Chemistry, University of Oxford, Oxford, OX1 3QZ, UK. weston.struwe@chem.ox.ac.uk.
Kevin PagelFree University Chemistry, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195, Berlin, Germany.
Justin L P BeneschDepartment of Chemistry, University of Oxford, Oxford, OX1 3QZ, UK.
David J HarveyOxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.
Matthew P CampbellBiomolecular Frontiers Research Centre, Macquarie University, Sydney, NSW 2109, Australia. matthew.campbell@mq.edu.au.ORCID 0000-0002-9525-792X

Funding

Biotechnology and Biological Sciences Research Council BB/L017733/1British Heart Foundation RG/07/012/24110
6 · The paper itself

Abstract

Ion mobility mass spectrometry (IM-MS) is a promising analytical technique for glycomics that separates glycan ions based on their collision cross section (CCS) and provides glycan precursor and fragment masses. It has been shown that isomeric oligosaccharide species can be separated by IM and identified on basis of their CCS and fragmentation. These results indicate that adding CCSs information for glycans and glycan fragments to searchable databases and analysis pipelines will increase identification confidence and accuracy. We have developed a freely accessible database, GlycoMob ( http://www.glycomob.org ), containing over 900 CCSs values of glycans, oligosaccharide standards and their fragments that will be continually updated. We have measured the absolute CCSs of calibration standards, biologically derived and synthetic N-glycans ionized with various adducts in positive and negative mode or as protonated (positive ion) and deprotonated (negative ion) ions.

Indexed as

Databases, ChemicalSoftwareGlycomicsMass SpectrometryPolysaccharidesPolysaccharidesDatabaseGlycanGlycoinformaticsGlycomicsIon mobilityMass spectrometry

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.