ArticleSchizophrenia research2015
Stigma related to labels and symptoms in individuals at clinical high-risk for psychosis.
Article in Schizophrenia research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
- Self-stigma in Serious Mental Illness: A Systematic Review of Frequency, Correlates, and Consequences.Schizophrenia bulletin · 2021Pooled it
- Positive Reframing of Psychosis Risk Reduces Social Stigma and Desire for Social Distance Among Adolescents: Moderating Roles of Prodromal Experiences, Sex, and Culture.Early intervention in psychiatry · 2026Trial
- Positive Reframing of Psychosis Risk is Perceived as Less Frightening and Stigmatising Than Negative Framing by Adolescents With and Without Prodromal Symptoms: An Experimental Simulated Feedback Study.Early intervention in psychiatry · 2025Trial
- "We Are Humans, and We Are People" - A Thematic Analysis Exploring the Disclosure and Help-Seeking Experiences of Young People Who Experience Voice-Hearing Within Mental Health Services in the UK.Clinical child psychology and psychiatry · 2026Article
- Structural and Functional Neuroimaging Biomarkers as Predictors of Psychosis Conversion in Ultra-High Risk Individuals: A Systematic Review.Brain sciences · 2026Review
- A Brief Engagement Intervention Adapted for Racial and Ethnic Minority Young Adults in Mental Health Services: Protocol for a Pilot Optimization Trial.JMIR research protocols · 2025Article
- Positive Reframing of Psychosis Risk Is Seen as More Beneficial and Less Harmful Than Negative Framing by Clinicians: An Experimental Videotaped Simulated Feedback Study.Schizophrenia bulletin · 2025Article
- Navigating the Maze: Caregiver Perspectives on Pathways to Mental Health Care for U.S. Youth at Clinical High Risk for Psychosis.Early intervention in psychiatry · 2025Article
- Ethical challenges in contemporary psychiatry: an overview and an appraisal of possible strategies and research needs.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Perceptions of stigma in youth at clinical high risk for psychosis and depressive symptomatology.Schizophrenia research · 2024Article
- Identification of Psychosis Risk and Diagnosis of First-Episode Psychosis: Advice for Clinicians.Psychology research and behavior management · 2024Review
- Development and evaluation of a risk algorithm predicting alcohol dependence after early onset of regular alcohol use.Addiction (Abingdon, England) · 2023Article
- The association between mental health stigma and face emotion recognition in individuals at risk for psychosis.Stigma and health · 2023Article
- Self-stigma and cognitive insight in individuals at ultra-high risk for psychosis.Frontiers in psychiatry · 2023Article
- Article
- Observational
- "Attitudes to voices": a survey exploring the factors influencing clinicians' intention to assess distressing voices and attitudes towards working with young people who hear voices.Frontiers in psychology · 2023Article
- Real-World Implementation of Precision Psychiatry: A Systematic Review of Barriers and Facilitators.Brain sciences · 2022Review
- Internalized stigma mediates the relation between psychosis-risk symptoms and subjective quality of life in a help-seeking sample.Schizophrenia research · 2022Article
- A qualitative study on identity in individuals at clinical high risk for psychosis: " … Why does it have to be one thing?".Psychiatric rehabilitation journal · 2022Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundDespite advances that the psychosis "clinical high-risk" (CHR) identification offers, risk of stigma exists. Awareness of and agreement with stereotypes has not yet been evaluated in CHR individuals. Furthermore, the relative stigma associated with symptoms, as opposed to the label of risk, is not known, which is critical because CHR identification may reduce symptom-related stigma.
methodsThirty-eight CHR subjects were ascertained using standard measures from the Center of Prevention and Evaluation/New York State Psychiatric Institute/ Columbia University. Labeling-related measures adapted to the CHR group included "stereotype awareness and self-stigma" ("Stereotype awareness", "Stereotype Agreement", "Negative emotions [shame]"), and a parallel measure of "Negative emotions (shame)" for symptoms. These measures were examined in relation to symptoms of anxiety and depression, adjusting for core CHR symptoms (e.g. attenuated psychotic symptoms).
resultsCHR participants endorsed awareness of mental illness stereotypes, but largely did not themselves agree with these stereotypes. Furthermore, CHR participants described more stigma associated with symptoms than they did with the risk-label itself. Shame related to symptoms was associated with depression, while shame related to the risk-label was associated with anxiety.
conclusionBoth stigma of the risk-label and of symptoms contribute to the experience of CHR individuals. Stereotype awareness was relatively high and labeling-related shame was associated with increased anxiety. Yet limited agreement with stereotypes indicated that labeling-related stigma had not fully permeated self-conceptions. Furthermore, symptom-related stigma appeared more salient overall and was linked with increased depression, suggesting that alleviating symptom-related shame via treating symptoms might provide major benefit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.