Evidence map›Paper›PMID 26314559›Full record

ArticleArthritis care & research2016

Association of Light-Intensity Physical Activity With Lower Cardiovascular Disease Risk Burden in Rheumatoid Arthritis.

Samannaaz S Khoja, Gustavo J Almeida, Mary Chester Wasko, Lauren Terhorst, Sara R Piva

Open access · greenAbstract readComparative Study
In one paragraph

Article in Arthritis care & research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Mobile App-Based Small-Group Physical Activity Intervention for Young African American Women: a Pilot Randomized Controlled Trial.Prevention science : the official journal of the Society for Prevention Research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samannaaz S KhojaUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Gustavo J AlmeidaUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Mary Chester WaskoWest Penn Hospital, Pittsburgh, Pennsylvania.
Lauren TerhorstUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Sara R PivaUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · USWestern Pennsylvania Hospital · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
Neuromuscular Electrical Stimulation in Individuals with Rheumatoid ArthritisK01HD058035 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PIVA, SARA R. · 2009 to 2013
$642k
NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1-RR-024153NICHD NIH HHS K01 HD058035NICHD NIH HHS K01-HD058035
6 · The paper itself

Abstract

objectiveTo characterize physical activity (PA) in individuals with rheumatoid arthritis (RA) and to determine the associations between PA participation at light to moderate intensities and cardiovascular disease risk factors, disability, and disease activity.

methodsThe cross-sectional study used data from 2 RA cohorts. PA was measured using an accelerometry-based activity monitor, recording minutes/day spent in sedentary (≤1 metabolic equivalent [MET]), very light (1.1-1.9 METs), light (2-2.9 METs), and moderate activities (≥3 METs). Cardiovascular markers included body mass index, blood pressure, insulin resistance, and lipid profile. Disability and disease activity were measured using the Health Assessment Questionnaire (HAQ) and the Disease Activity Score in 28 joints (DAS28), respectively. Associations between PA at each intensity level and health markers were assessed by multiple linear regression models, adjusted for age, sex, and cohort.

resultsNinety-eight subjects (mean ± SD age 58 ± 9 years, 85% female) were included. Subjects spent 9.8 hours/day being sedentary, 3.5 hours/day engaged in very light PA, 2.1 hours/day engaged in light PA, and 35 minutes/day engaged in moderate PA. Only 17% were physically active (≥150 minutes/week of moderate PA in 10-minute bouts). Regression models showed that very light, light, and moderate PA were inversely associated with most cardiovascular disease risk factors and HAQ and DAS28 scores (R(2) Δ range 0.04-0.52, P < 0.05). The associations between PA and cardiovascular disease markers were either equivalent or stronger at very light and light intensities, as compared to moderate intensity.

conclusionIndividuals with RA are mostly active at very light and light intensities. PA at these intensity levels associates favorably with cardiovascular markers and lower disability and disease activity in RA.

Indexed as

Motor ActivityRisk Reduction BehaviorSedentary BehaviorActigraphyAgedArthritis, RheumatoidCardiovascular DiseasesCross-Sectional StudiesDisability EvaluationFemaleHealth StatusHumansMaleMiddle AgedRandomized Controlled Trials as TopicRisk Assessment

Identifiers

PMID26314559
PMCPMC6217964
OpenAlexW2340399078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.