ArticlePloS one2015
MiR-378b Promotes Differentiation of Keratinocytes through NKX3.1.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- White adipose tissues and skeletal muscles as a target of chrysin during the treatment of obesity in rats.Scientific reports · 2025Article
- Direct Lineage Reprogramming for Induced Keratinocyte Stem Cells: A Potential Approach for Skin Repair.Stem cells translational medicine · 2023Review
- microRNA-378b regulates ethanol-induced hepatic steatosis by targeting CaMKK2 to mediate lipid metabolism.Bioengineered · 2021Article
- Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B antisense RNA 1 induces the proliferation and migration of colorectal cancer by miR-378b/CAPRIN2 axis.Bioengineered · 2021Article
- MiR-378b ModulatesPathogens (Basel, Switzerland) · 2021Article
- Upregulated microRNA-126 induces apoptosis of dental pulp stem cell via mediating PTEN-regulated Akt activation.Journal of clinical laboratory analysis · 2021Article
- Transcriptomic and Morphological Analysis of Cells Derived from Porcine Buccal Mucosa-Studies on an In Vitro Model.Animals : an open access journal from MDPI · 2020Article
- The Role of MicroRNAs in Epidermal Barrier.International journal of molecular sciences · 2020Review
- miR-378b Regulates Insulin Sensitivity by Targeting Insulin Receptor and p110α in Alcohol-Induced Hepatic Steatosis.Frontiers in pharmacology · 2020Article
- miR-224-5p protects dental pulp stem cells from apoptosis by targeting Rac1.Experimental and therapeutic medicine · 2020Article
- Analysis of microRNA expression in peripheral blood monocytes of three Traditional Chinese Medicine (TCM) syndrome types in psoriasis patients.Chinese medicine · 2020Article
- Long Noncoding RNA CDKN2B-AS1 Facilitates Lung Cancer Development Through Regulating miR-378b/NR2C2.OncoTargets and therapy · 2020Article
- miR29a and miR378b Influence CpG-Stimulated Dendritic Cells and Regulate cGAS/STING Pathway.Vaccines · 2019Article
- Article
- A unique insight into the MiRNA profile during genital chlamydial infection.BMC genomics · 2019Article
- The Homeodomain Transcription Factor NKX3.1 Modulates Bladder Outlet Obstruction Induced Fibrosis in Mice.Frontiers in pediatrics · 2019Article
- H19 lncRNA regulates keratinocyte differentiation by targeting miR-130b-3p.Cell death & disease · 2017Article
- Mouse-specific up-regulation ofFEBS open bio · 2016Article
- MicroRNA-93 inhibits ischemia-reperfusion induced cardiomyocyte apoptosis by targeting PTEN.Oncotarget · 2016Article
- Regulation of Srpr Expression by miR-330-5p Controls Proliferation of Mouse Epidermal Keratinocyte.PloS one · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNA (miRNA) is a kind of short non-coding RNA, involved in various cellular processes. During keratinocyte differentiation, miRNAs act as important regulators. In this study, we demonstrated by microarray assay that the expression of miR-378b significantly increased during keratinocytes differentiation. Our findings showed that miR-378b could inhibit proliferation, migration and differentiation in keratinocytes. Luciferase reporter assays showed that miR-378b directly target NKX3.1. Silencing of NKX3.1 could coincide with the effects of miR-24 overexpression. In conclusion, our results demonstrate miR-378b promote keratinocytes differentiation by targeting NKX3.1. Manipulation of miR-378b may afford a new strategy to clinic treatment of skin injury and repair.
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