ArticlePloS one2015
Depression Dimensions: Integrating Clinical Signs and Symptoms from the Perspectives of Clinicians and Patients.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Rates of Depression in Children and Adolescents With ADHD: A Systematic Review and Meta-Analysis.Journal of attention disorders · 2025Pooled it
- Actigraphically measured psychomotor slowing in depression: systematic review and meta-analysis.Psychological medicine · 2022Pooled it
- Developing and validating a short version of the multidimensional depression scale in asian adolescents sample using rasch analysis.Scientific reports · 2026Article
- In-depth psychometric evaluation of the PsychQOL questionnaire: factor structure and ROC analysis.Frontiers in psychology · 2026Article
- Discrimination, depressive symptoms, and prescription opioid misuse among adults with chronic pain who engage in hazardous drinking.The American journal of drug and alcohol abuse · 2026Article
- Differential associations of passively sensed behaviors with in-vivo depression symptoms.Journal of psychopathology and clinical science · 2025Article
- Factor structure and measurement invariance of the Mood and Feelings Questionnaire: a cross-cultural study among Thai and British adolescents.European child & adolescent psychiatry · 2024Article
- Measurement invariance of the Center for Epidemiologic Studies Scale-Depression within and across six diverse intervention trials.Psychological assessment · 2023Article
- Dimensions of the Hamilton Depression Rating Scale Correlate with Impulsivity and Personality Traits among Youth Patients with Depression.Journal of clinical medicine · 2023Article
- The diagnostic and predictive potential of personality traits and coping styles in major depressive disorder.BMC psychiatry · 2022Article
- Clinical Guidelines of the Egyptian Psychiatric Association for the Management of Treatment-Resistant Unipolar Depression in Egypt.Frontiers in psychiatry · 2022Article
- Motor abnormalities, depression risk, and clinical course in adolescence.Biological psychiatry global open science · 2022Article
- The factor structure of depressive symptoms in patients with obesity enrolled in the RAINBOW clinical trial.Journal of affective disorders · 2021Article
- Factors associated with psychological stress and distress among Korean adults: the results from Korea National Health and Nutrition Examination Survey.Scientific reports · 2020Article
- Exploratory and confirmatory factor analyses and invariance assessment of the perceived powerlessness scale among youth in Baltimore.Journal of health psychology · 2020Article
- Inflammation and the dimensions of depression: A review.Frontiers in neuroendocrinology · 2020Review
- An Examination of Psychomotor Disturbance in Current and Remitted MDD: An RDoC Study.Journal of psychiatry and brain science · 2020Article
- Adapting the Goal Attainment Approach for Major Depressive Disorder.Neurology and therapy · 2019Article
- Article
- Different spatial patterns of brain atrophy and global functional connectivity impairments in major depressive disorder.Brain imaging and behavior · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have recognized that depression is a multidimensional construct, although the scales that are currently available have been shown to be limited in terms of the ability to investigate the multidimensionality of depression. The objective of this study is to integrate information from instruments that measure depression from different perspectives-a self-report symptomatic scale, a clinician-rated scale, and a clinician-rated scale of depressive signs-in order to investigate the multiple dimensions underlying the depressive construct.
methodsA sample of 399 patients from a mood disorders outpatient unit was investigated with the Beck Depression Inventory (BDI), the Hamilton Depression Rating Scale (HDRS), and the Core Assessment of Psychomotor Change (CORE). Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) were used to investigate underlying dimensions of depression, including item level analysis with factor loadings and item thresholds.
resultsA solution of six depression dimensions has shown good-fit to the data, with no cross-loading items, and good interpretability. Item-level analysis revealed that the multidimensional depressive construct might be organized into a continuum of severity in the following ascending order: sexual, cognitive, insomnia, appetite, non-interactiveness/motor retardation, and agitation.
conclusionAn integration of both signs and symptoms, as well as the perspectives of clinicians and patients, might be a good clinical and research alternative for the investigation of multidimensional issues within the depressive syndrome. As predicted by theoretical models of depression, the melancholic aspects of depression (non-interactiveness/motor retardation and agitation) lie at the severe end of the depressive continuum.
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