SynthesisNPJ primary care respiratory medicine2015
Effectiveness of case finding strategies for COPD in primary care: a systematic review and meta-analysis.
Synthesis in NPJ primary care respiratory medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03355677 (A Clinical Interventional Study Into Airways Disease Case Finding and Complex Case Management), which is not on this map. Cited by 38 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Clinical Interventional Study Into Airways Disease Case Finding and Complex Case Management
Who cites it
38 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Prevalence of COPD in other long-term conditions: a systematic meta review.BMC pulmonary medicine · 2026Pooled it
- Economic evaluations of screening and case-finding for Chronic Obstructive Pulmonary Disease (COPD): a systematic review.NPJ primary care respiratory medicine · 2026Pooled it
- Prevalence of chronic respiratory disease using case-finding tools in adults living with noncommunicable disease in low- and middle-income countries: a systematic review.BMC pulmonary medicine · 2025Pooled it
- Application of Discrete Event Simulation Models for COPD Management: A Systematic Review.International journal of chronic obstructive pulmonary disease · 2025Pooled it
- Prevalence of chronic obstructive pulmonary disease and chronic bronchitis in eight countries: a systematic review and meta-analysis.Bulletin of the World Health Organization · 2022Pooled it
- Case-finding for common mental disorders in primary care using routinely collected data: a systematic review.Social psychiatry and psychiatric epidemiology · 2019Pooled it
- Characterizing undiagnosed chronic obstructive pulmonary disease: a systematic review and meta-analysis.Respiratory research · 2018Pooled it
- Opportunistic screening for COPD among socially marginalized patients.BMC pulmonary medicine · 2024Trial
- Review
- Community-Based Case-Finding for Chronic Obstructive Pulmonary Disease and Self-Management Education in Partnership with Faith-Based Organizations.International journal of chronic obstructive pulmonary disease · 2026Article
- Sex-Based Disparities in Clinical Burden and Diagnostic Delay in COPD: Insights from Primary Care.Journal of clinical medicine · 2025Article
- The Use of Lung Cancer Screening to Increase Chronic Obstructive Pulmonary Disease Diagnosis in Veterans Affairs Primary Care.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Article
- A Two-Staged, Risk-Stratified Strategy Combining FEVRespirology (Carlton, Vic.) · 2025Observational
- Article
- Factors associated with undiagnosed COPD in patients hospitalised for severe COPD exacerbation.BMJ open respiratory research · 2024Article
- Spirometry practice by French general practitioners between 2010 and 2018 in adults aged 40 to 75 years.NPJ primary care respiratory medicine · 2023Article
- Identification of key opportunities for optimising the management of high-risk COPD patients in the UK using the CONQUEST quality standards: an observational longitudinal study.The Lancet regional health. Europe · 2023Article
- Different Case Finding Approaches to Optimise COPD Diagnosis: Evidence from the RADICALS Trial.International journal of chronic obstructive pulmonary disease · 2023Article
- Current Progress of COPD Early Detection: Key Points and Novel Strategies.International journal of chronic obstructive pulmonary disease · 2023Review
- Identifying airway obstruction in primary care: is there a role for physiotherapists?BMC primary care · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundChronic obstructive pulmonary disease (COPD) is widely underdiagnosed, but the most effective approach for identifying these patients is unknown.
aimsThe aim of this study was to summarise and compare the effectiveness of different case finding approaches for undiagnosed COPD in primary care.
methodsA systematic review of primary studies of any design evaluating case finding strategies for COPD in primary care among individuals aged ⩾35 years with no prior diagnosis was conducted. Medline, Embase and other bibliographic databases were searched from 1997 to 2013, and methodological quality was assessed using standard tools. Results were described and meta-analysis of the uptake and yield from different approaches was performed where there was sufficient homogeneity.
resultsThree randomised controlled trials (RCTs), 1 controlled trial and 35 uncontrolled studies were identified that assessed the identification of new cases of COPD through systematic case finding. A range of approaches were used including pre-screening with questionnaires (n=13) or handheld flow meters (n=5) or direct invitation to diagnostic spirometry (n=30). Overall, any approach identified more undiagnosed COPD compared with usual care. Targeting those at higher risk (e.g., smokers) and pre-screening (e.g., using questionnaires) is likely to increase the yield. However, studies were heterogeneous and were limited by a lack of comparison groups, inadequate reporting and diversity in the definition of COPD, which limited our ability to draw firm conclusions.
conclusionsThere is extensive heterogeneity among studies evaluating case finding strategies for COPD, with few RCTs. Well-conducted RCTs comparing case finding approaches are needed to identify the most effective target population, recruitment strategy and screening tests, using a clinical definition of COPD, and addressing the limitations highlighted in this review. There is also a need to evaluate the impact of case finding on clinical care and patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.