Evidence map›Paper›PMID 26313262›Full record

ArticleSoft matter2015

Pseudotannins self-assembled into antioxidant complexes.

H A Cheng, C T Drinnan, N Pleshko, O Z Fisher

Abstract read
In one paragraph

Article in Soft matter, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

H A ChengDepartment of Bioengineering, Temple University, 1947 N 12th Street, Philadelphia, PA, USA. ozf@temple.edu.
C T Drinnan
N Pleshko
O Z Fisher
Temple College · USPhiladelphia University · USTemple University · US

Funding

Iron Oxide Based Polymer Nanocomplex for Functional Detection of AtherosclerosisR21EB017504 · NIBIB · STATE UNIVERSITY OF NY,BINGHAMTON · PI DOIRON, AMBER L, FISHER, OMAR Z · 2013 to 2014
$413k
NIBIB NIH HHS 1R21EB017504NIBIB NIH HHS R21 EB017504
6 · The paper itself

Abstract

Natural tannins are attractive as building blocks for biomaterials due to their antioxidant properties and ability to form interpolymer complexes (IPCs) with other macromolecules. One of the major challenges to tannin usage in biomedical applications is their instability at physiological conditions and a lack of control over the purity and reactivity. Herein, we report the synthesis and characterization of tannin-like polymers with controlled architecture, reactivity, and size. These pseudotannins were synthesized by substituting linear dextran chains with gallic, resorcylic, and protocatechuic pendant groups to mimic the structure of natural hydrolysable tannins. We demonstrate that these novel materials can self-assemble to form reductive and colloidally stable nanoscale and microscale particles. Specifically, the synthesis, turbidity, particle size, antioxidant power, and cell uptake of IPCs derived from pseudotannins and poly(ethylene glycol) was evaluated.

Indexed as

AntioxidantsCell Line, TumorCell SurvivalDynamic Light ScatteringHumansMicroscopy, ConfocalMolybdenumNephelometry and TurbidimetryParticle SizePolyethylene GlycolsSpectroscopy, Fourier Transform InfraredTanninsTungsten CompoundsAntioxidantsFolin's phenol reagentMolybdenumPolyethylene GlycolsTanninsTungsten Compounds

Identifiers

PMID26313262
PMCPMC4589535
OpenAlexW1842419540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.