Evidence map›Paper›PMID 26312756›Full record

ReviewPLoS genetics2015

Of Fighting Flies, Mice, and Men: Are Some of the Molecular and Neuronal Mechanisms of Aggression Universal in the Animal Kingdom?

Amanda L Thomas, Shaun M Davis, Herman A Dierick

Open access · goldAbstract readReview
In one paragraph

Review in PLoS genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Article
  3. The need for unbiased genetic screens to dissect aggression inFrontiers in behavioral neuroscience · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Animal Models of (or for) Aggression Reward, Addiction, and Relapse: Behavior and Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Review
  9. Conserved transcriptomic profiles underpin monogamy across vertebrates.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amanda L ThomasDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.
Shaun M DavisDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.
Herman A DierickDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America; Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America; Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America.
Baylor College of Medicine · US

Funding

Serotonergic modulation of aggression in Drosophila melanogasterR01GM109938 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI DIERICK, HERMAN A · 2015 to 2019
$1.5M
NIGMS NIH HHS R01 GM109938
6 · The paper itself

Abstract

Aggressive behavior is widespread in the animal kingdom, but the degree of molecular conservation between distantly related species is still unclear. Recent reports suggest that at least some of the molecular mechanisms underlying this complex behavior in flies show remarkable similarities with such mechanisms in mice and even humans. Surprisingly, some aspects of neuronal control of aggression also show remarkable similarity between these distantly related species. We will review these recent findings, address the evolutionary implications, and discuss the potential impact for our understanding of human diseases characterized by excessive aggression.

Indexed as

AggressionAnimalsBehavior, AnimalBiological EvolutionDrosophila melanogasterHumansMiceNeuronsNeuropeptidesReceptors, Cytoplasmic and NuclearTranscription, GeneticNeuropeptidesNr2e1 protein, mouseReceptors, Cytoplasmic and Nuclear

Identifiers

PMID26312756
PMCPMC4551476
OpenAlexW1609661230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.