Kick it up a notch: Notch signaling and kidney fibrosis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

24 citing papers in PubMed.

1. Nanoparticles in the Treatment of Renal Fibrosis.International journal of nanomedicine · 2026
   Review
2. Simvastatin Mitigates Kidney Injury via Inhibition of the TNF-α/α-SMA Signaling Pathway in a Subtotal Nephrectomy Model.Journal of experimental pharmacology · 2026
   Article
3. Spatial and Temporal Expression Patterns of EDA2R, PCDH9, and TRAF7 inInternational journal of molecular sciences · 2025
   Article
4. miRNA and mRNA Signatures in Human Acute Kidney Injury Tissue.The American journal of pathology · 2025
   Article
5. Notch signaling in diabetic kidney disease: recent progress.Frontiers in endocrinology · 2025
   Review
6. Serelaxin Alleviates Fibrosis in Thyroid-Associated Ophthalmopathy via the Notch Pathway.International journal of molecular sciences · 2023
   Article
7. ADAM10 and ADAM17, Major Regulators of Chronic Kidney Disease Induced Atherosclerosis?International journal of molecular sciences · 2023
   Review
8. COVID-19 and fibrosis: Mechanisms, clinical relevance, and future perspectives.Drug discovery today · 2022
   Review
9. A Homozygous Dab1Biomolecules · 2021
   Article
10. Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression.Journal of the American Society of Nephrology : JASN · 2020
    Article
11. The efficacy of taking traditional Chinese medicine orally in renal interstitial fibrosis: A protocol for a systematic review and meta-analysis.Medicine · 2020
    Article
12. The Role of Notch3 Signaling in Kidney Disease.Oxidative medicine and cellular longevity · 2020
    Review
13. Blockade of ERK1/2 by U0126 alleviates uric acid-induced EMT and tubular cell injury in rats with hyperuricemic nephropathy.American journal of physiology. Renal physiology · 2019
    Article
14. Nrf2-Heme Oxygenase-1 Attenuates High-Glucose-Induced Epithelial-to-Mesenchymal Transition of Renal Tubule Cells by Inhibiting ROS-Mediated PI3K/Akt/GSK-3Journal of diabetes research · 2019
    Article
15. Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.PLoS biology · 2018
    Article
16. Renal ADAM10 and 17: Their Physiological and Medical Meanings.Frontiers in cell and developmental biology · 2018
    Article
17. Scar management in burn injuries using drug delivery and molecular signaling: Current treatments and future directions.Advanced drug delivery reviews · 2018
    Review
18. Signalling pathways involved in hypoxia-induced renal fibrosis.Journal of cellular and molecular medicine · 2017
    Review
19. Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction.BMC systems biology · 2017
    Article
20. Sonic hedgehog signaling in kidney fibrosis: a master communicator.Science China. Life sciences · 2016
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as