ArticleThe open respiratory medicine journal2015
Humidification on Ventilated Patients: Heated Humidifications or Heat and Moisture Exchangers?
Article in The open respiratory medicine journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Demographic, perioperative, biochemical and illness-severity predictors of thirst in critically ill patients: a systematic review and meta-analysis.Internal medicine journal · 2026Pooled it
- Airway warming devices in the context of single and multimodal strategies for intraoperative hypothermia: a network meta-analysis.Systematic reviews · 2026Pooled it
- Effect of active airway warming with a heated-humidified breathing circuit on core body temperature in patients under general anesthesia: a systematic review and meta-analysis with trial sequential analysis.Korean journal of anesthesiology · 2023Pooled it
- High-flow Nasal Cannula Over Non-invasive Ventilation in Preventing Reintubation: Signal Bias or Both?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- How can the collaboration between manufacturers of medical devices and bedside clinicians lead to improved applications of the devices?Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2026Article
- Use of artificial humidification during non-invasive mechanical ventilation in patients with acute respiratory failure: a narrative review.Journal of thoracic disease · 2025Review
- Humidification during Invasive and Non-Invasive Ventilation: A Starting Tool Kit for Correct Setting.Medical sciences (Basel, Switzerland) · 2024Review
- Interfaces, Circuits and Humidifiers.Frontiers in pediatrics · 2020Review
- Impact of leaks and ventilation parameters on the efficacy of humidifiers during home ventilation for tracheostomized patients: a bench study.BMC pulmonary medicine · 2019Article
- Respiratory Care for the Ventilated Neonate.Canadian respiratory journal · 2018Review
- Respiratory gas conditioning with filters/ heat and moisture exchangers can increase the duration of hyperthermia in patients under mechanical ventilation.Medical gas researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The normal physiology of conditioning of inspired gases is altered when the patient requires an artificial airway access and an invasive mechanical ventilation (IMV). The endotracheal tube (ETT) removes the natural mechanisms of filtration, humidification and warming of inspired air. Despite the noninvasive ventilation (NIMV) in the upper airways, humidification of inspired gas may not be optimal mainly due to the high flow that is being created by the leakage compensation, among other aspects. Any moisture and heating deficit is compensated by the large airways of the tracheobronchial tree, these are poorly suited for this task, which alters mucociliary function, quality of secretions, and homeostasis gas exchange system. To avoid the occurrence of these events, external devices that provide humidification, heating and filtration have been developed, with different degrees of evidence that support their use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.