Evidence map›Paper›PMID 26311848›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2015

The growing importance of mitochondrial calcium in health and disease.

Liron Boyman, George S B Williams, W J Lederer

Abstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Calcium influx through the mitochondrial calcium uniporter holocomplex, MCUJournal of molecular and cellular cardiology · 2021
    Review
  5. Article
  6. Regulation of Mitochondrial ATP Production: CaTrends in molecular medicine · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Liron BoymanCenter for Biomedical Engineering and Technology and Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201.
George S B WilliamsCenter for Biomedical Engineering and Technology and Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201.
W J LedererCenter for Biomedical Engineering and Technology and Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201 jlederer@umaryland.edu.

Funding

Multiscale spatiotemporal modeling of cardiac mitochondriaU01HL116321 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JAFRI, MOHSIN SALEET, LEDERER, WILLIAM JONATHAN · 2014 to 2018
$3.5M
Mitochondrial Calcium Signaling in HeartK25HL125762 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI WILLIAMS, GEORGE S. B. · 2015 to 2019
$809k
NHLBI NIH HHS K25 HL125762NHLBI NIH HHS K25HL125762NHLBI NIH HHS U01 HL116321NHLBI NIH HHS U01HL116321
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Oxidative StressAnimalsCalciumHeart FailureMitochondria, HeartReactive Oxygen SpeciesCalciumReactive Oxygen Species

Identifiers

PMID26311848
PMCPMC4568708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.