ReviewAdvances in chronic kidney disease2015
GFR Estimating Equations and Liver Disease.
Review in Advances in chronic kidney disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 62 citations in OpenAlex.
- Early detection of acute kidney injury in the perioperative period of liver transplant with neutrophil gelatinase-associated lipocalin.BMC nephrology · 2019Trial
- Metabolomic and proteomic analyses of renal function after liver transplantation.Frontiers in transplantation · 2025Article
- Optimizing Piperacillin Dosing in Pediatric Liver Transplant Recipients: A Case Series.Pediatric transplantation · 2024Article
- Angiotensin II type 1 receptor antibodies and native kidney function in pediatric liver and intestinal transplant recipients.Pediatric nephrology (Berlin, Germany) · 2023Article
- Serum cystatin C and βeta-2 microglobulin as potential biomarkers in children with lupus nephritis.Archives of rheumatology · 2023Article
- Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination.Drug metabolism and disposition: the biological fate of chemicals · 2023Article
- Increased Renal Expression of Complement Components in Patients With Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination.Toxicological sciences : an official journal of the Society of Toxicology · 2022Article
- Peri-operative risk factors of chronic kidney disease after liver transplantation.Journal of nephrology · 2022Article
- Association between liver stiffness measurement by transient elastography and chronic kidney disease.Medicine · 2022Article
- Serum creatinine as an indicator of lean body mass in vegetarians and omnivores.Frontiers in nutrition · 2022Article
- [Clinical Value of Cystatin C-Based Estimated Glomerular Filtration Rate in Assessing Short-Term Mortality in Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failure Treated with Artificial Liver Support System].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2021Article
- Global strategy for the diagnosis and management of acute kidney injury in patients with liver cirrhosis.United European gastroenterology journal · 2021Review
- Tissue/Biofluid Specific Molecular Cartography ofFrontiers in cellular and infection microbiology · 2021Article
- A Multicenter Evaluation of Vancomycin-Associated Acute Kidney Injury in Hospitalized Patients with Acute Bacterial Skin and Skin Structure Infections.Infectious diseases and therapy · 2020Article
- Evaluation of Neutrophil Gelatinase-Associated Lipocalin and Cystatin C in Early Diagnosis of Chronic Kidney Disease in the Absence of the Gold Standard.Galen medical journal · 2020Article
- [Laboratory tests for kidney disease].Der Internist · 2019Article
- Clinical characteristics of sepsis-induced acute kidney injury in patients undergoing continuous renal replacement therapy.Renal failure · 2018Article
- Methods of Estimating Kidney Function for Drug Dosing in Special Populations.Clinical pharmacokinetics · 2018Review
- REnal Flow and Microstructure AnisotroPy (REFMAP) MRI in Normal and Peritumoral Renal Tissue.Journal of magnetic resonance imaging : JMRI · 2018Article
- Establishing the presence or absence of chronic kidney disease: Uses and limitations of formulas estimating the glomerular filtration rate.World journal of methodology · 2017Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
It is important to accurately assess the glomerular filtration rate (GFR) of patients with liver disease to deliver care and allocate organs for transplantation in a way that improves outcomes. The most commonly used methods to estimate GFR in this population are based on creatinine, which is biased by these patients' low creatinine production and potentially by elevated serum bilirubin and decreased albumin levels. None of the creatinine-based estimated glomerular filtration rate (eGFR) equations have been specifically modified for a population with liver disease, and even measurement of a 24-hour creatinine clearance has limitations. In liver disease, all creatinine-based estimates of GFR overestimate gold standard-measured GFR, and the degree of overestimation is highest at lower measured GFR values and in more severe liver disease. Cystatin C-based eGFR has shown promise in general population studies by demonstrating less bias than creatinine-based eGFR and improved association with clinically important outcomes, but results in the liver disease population have been mixed, and further studies are necessary. Ultimately, specific eGFR equations for liver disease or novel methods for estimating GFR may be necessary. However, for now, the limitations of currently available methods need to be appreciated to understand kidney function in liver disease.
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