Trial reportBMC neurology2015
Improving medication adherence in stroke patients through Short Text Messages (SMS4Stroke)-study protocol for a randomized, controlled trial.
Trial report in BMC neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01986023 (A Randomized Controlled SMS Intervention For Improving Medication Adherence in Adult Stroke Patients), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled SMS Intervention For Improving Medication Adherence in Adult Stroke Patients
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2024Pooled it
- Mobile phone text messaging to improve medication adherence in secondary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2017Pooled it
- Trial
- Trial
- An intervention study on the secondary prevention medication adherence of ischemic stroke patients based on the protection motivation theory combined with medication literacy education in the AI-HEALS: a randomized controlled trial protocol.Frontiers in public health · 2025Article
- Effect of mobile-based self-management application on stroke outcomes: a study protocol for triple blinded randomized controlled trial.BMC medical informatics and decision making · 2022Article
- Effect of core stabilization exercises in addition to conventional therapy in improving trunk mobility, function, ambulation and quality of life in stroke patients: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2022Article
- Article
- Medicines containing codeine: perspectives of medical professionals in the Republic of Ireland.Irish journal of medical science · 2017Article
- High-quality Health Information Provision for Stroke Patients.Chinese medical journal · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
backgroundStroke is a major cause of morbidity and mortality, especially in low and middle income countries. Medical management is the mainstay of therapy to prevent recurrence of stroke. Current estimates are that only 1 in 6 patients have perfect adherence to medication schedules. Using SMS (Short Messaging Service) as reminders to take medicines have been used previously for diseases such as diabetes and HIV with moderate success. We aim to explore the effectiveness and acceptability of SMS in increasing adherence to medications in patients with stroke.
methodsThis will be a randomized, controlled, assessor blinded single center superiority trial. Adult participants with access to a cell phone and a history of stroke longer than 1 month on multiple risk modifying medications will be selected from Neurology and Stroke Clinic. They will be randomized into two parallel groups in a 1:1 ratio via block technique with one group receiving the standard of care as per institutional guidelines while the parallel group receiving SMS reminders for each dose of medicine in addition to the standard of care. In addition intervention group will receive messages for lifestyle changes, medication information, risk factors and motivation for medication adherence. These will bemodeled on Social Cognitive Theory and Health Belief Model and will be categorized by Michies Taxonomy of Behavioral Change Communication. Patient compliance to medicines will be measured at baseline and then after 2 months in each group by using the Morisky Medication Adherence Scale. The change in compliance to medication regimen after the intervention and the difference between the two groups will be used to determine the effectiveness of SMS reminders as a tool to increase medication compliance. The acceptability of the SMS will be determined by a tool designed for this study whose attributes are based Rogers Diffusion of innovation theory. A sample size of 86 participants in each arm will be sufficient to detect a difference of 1 point on the MMAS with a power of 90 % and significance level of 5 % between the two groups; using an attrition rate of 15 %, 200 participants in all will be randomized. DISCUSSION: The SMS for Stroke Study will provide evidence for feasibility and effectiveness of SMS in improving post stroke medication adherence in an LMIC setting.
trial registrationhttps://clinicaltrials.gov/ct2/show/NCT01986023 11 /11/2013.
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