ArticleOrthopaedic surgery2015
Reconstruction of Segmental Stability of Goat Cervical Spine with Poly (D, L-lactic acid) Cage.
Article in Orthopaedic surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Clinical Outcomes of N-HA/pa66 and Titanium Mesh in the Treatment of Lower Cervical Spine Fractures and Dislocations During an 8-Year Follow-Up Period.Orthopaedic surgery · 2025Article
- Main elements of current spine biomechanics research: model, installation and test data.Frontiers in bioengineering and biotechnology · 2025Review
- BIOABSORBABLE CAGES IN SPINAL FUSION IN AN ANIMAL MODEL: A SYSTEMATIC REVIEW AND META-ANALYSIS.Acta ortopedica brasileira · 2025Review
- Anterior Cervical Corpectomy and Fusion and Anterior Cervical Discectomy and Fusion Using Titanium Mesh Cages for Treatment of Degenerative Cervical Pathologies: A Literature Review.Medical science monitor : international medical journal of experimental and clinical research · 2018Review
- [Design and research progress of zero profile cervical Interbody cage].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the characteristics of inter body fusion after using an established poly (D, L-lactic acid) (PDLLA) cage, a titanium cage or autologous tricortical iliac crest graft in a goat cervical spine model in vivo.
methodsTwenty-four goats were assigned to three groups: PDLLA cage group (n = 8), titanium alloy cage group (n = 8) and autologous iliac bone group (n = 8), and underwent C3-4 discectomy and fusion with the allocated procedure. Radiography was performed pre- and post-operatively and after 1, 2, 4, 8 and 12 weeks and disc space height (DSH), intervertebral angle (IVA), and lordosis angle (LA) measured at these time points. After 12 weeks, the goats were killed and fusion sites removed. Biomechanical testing was performed in flexion, extension, axial rotation, and lateral bending to determine the stiffness and range of motion (ROM). All specimens were also assessed histomorphologically.
resultsThe IVA of PDLLA cage four weeks postoperatively and DSH eight and twelve weeks postoperatively were significantly greater than that of autologous iliac bone graft (P < 0.05). The LA values did not differ significantly between groups. The stiffness of both types of cages for axial rotation and lateral bending, and ROM for every movement, were significantly greater than that of the autologous iliac bone graft group (P < 0.05). PDLLA and titanium cages did not differ significantly (P > 0.05). Radiographic and histomorphological assessment showed better fusion in the cage than the autologous bone groups.
conclusionThe PDLLA cage can provide good intervertebral distract ability and enough biomechanical stability for cervical fusion.
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