ReviewMolecular neurobiology2016
Organotypic Spinal Cord Culture: a Proper Platform for the Functional Screening.
Review in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- An ex vivo injury model perfused with whole blood reveals rapid mechanical and transcriptional changes within the spinal cord.Bioengineering & translational medicine · 2026Article
- Cryogel scaffolds for localised delivery of lipopolysaccharide in organotypic spinal cord slice cultures: A novelMaterials today. Bio · 2025Article
- Modeling demyelination and endogenous remyelination in spinal cordFrontiers in cellular neuroscience · 2024Article
- ST2-Conditioned Medium Fosters Dorsal Horn Cell Excitability and Synaptic Transmission in Cultured Mouse Spinal Cord.Stem cell reviews and reports · 2023Article
- An In Vitro and Ex Vivo Analysis of the Potential of GelMA Hydrogels as a Therapeutic Platform for Preclinical Spinal Cord Injury.Advanced healthcare materials · 2023Article
- Hydrogel-in-hydrogel live bioprinting for guidance and control of organoids and organotypic cultures.Nature communications · 2023Article
- Organotypic spinal cord cultures: An <em>in vitro</em> 3D model to preliminary screen treatments for spinal muscular atrophy.European journal of histochemistry : EJH · 2021Article
- Decellularized skeletal muscles display neurotrophic effects in three-dimensional organotypic cultures.Stem cells translational medicine · 2020Article
- Article
- Neuregulin 1 Reduces Motoneuron Cell Death and Promotes Neurite Growth in anFrontiers in cellular neuroscience · 2017Article
- Valproic acid preserves motoneurons following contusion in organotypic spinal cord slice culture.The journal of spinal cord medicine · 2017Article
- Hydrogel and neural progenitor cell delivery supports organotypic fetal spinal cord development in anJournal of tissue engineeringArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent improvements in organotypic slice culturing and its accompanying technological innovations have made this biological preparation increasingly useful ex vivo experimental model. Among organotypic slice cultures obtained from various central nervous regions, spinal cord slice culture is an absorbing model that represents several unique advantages over other current in vitro and in vivo models. The culture of developing spinal cord slices, as allows real-time observation of embryonic cells behaviors, is an instrumental platform for developmental investigation. Importantly, due to the ability of ex vivo models to recapitulate different aspects of corresponding in vivo conditions, these models have been subject of various manipulations to derive disease-relevant slice models. Moreover spinal cord slice cultures represent a potential platform for screening of different pharmacological agents and evaluation of cell transplantation and neuroregenerative materials. In this review, we will focus on studies carried out using the ex vivo model of spinal cord slice cultures and main advantages linked to practicality of these slices in both normal and neuropathological diseases and summarize them in different categories based on application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.