Evidence map›Paper›PMID 26310582›Full record

ArticleEuropean radiology2016

Diffusion-weighted imaging of breast tumours at 3 Tesla and 7 Tesla: a comparison.

S Gruber, L Minarikova, K Pinker, O Zaric, M Chmelik, B Strasser, P Baltzer, T Helbich, S Trattnig, W Bogner

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Diffusion-weighted breast MRI: Clinical applications and emerging techniques.Journal of magnetic resonance imaging : JMRI · 2017
    Review
  8. The potential of multiparametric MRI of the breast.The British journal of radiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

S GruberMRCE, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Lazarettgasse 14, 1090, Vienna, Austria.
L MinarikovaMRCE, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Lazarettgasse 14, 1090, Vienna, Austria.
K PinkerDivision of Molecular and Gender Imaging, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Vienna, Austria.
O ZaricMRCE, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Lazarettgasse 14, 1090, Vienna, Austria.
M ChmelikMRCE, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Lazarettgasse 14, 1090, Vienna, Austria.
B StrasserMRCE, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Lazarettgasse 14, 1090, Vienna, Austria.
P BaltzerDivision of Molecular and Gender Imaging, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Vienna, Austria.
T HelbichDivision of Molecular and Gender Imaging, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Vienna, Austria.
S TrattnigMRCE, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Lazarettgasse 14, 1090, Vienna, Austria. siegfried.trattnig@meduniwien.ac.at.
W BognerMRCE, Department of Biomedical imaging and Image-Guided Therapy, Medical University Vienna, Lazarettgasse 14, 1090, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare bilateral diffusion-weighted MR imaging (DWI) at 3 T and 7 T in the same breast tumour patients.

methodsTwenty-eight patients were included in this IRB-approved study (mean age 56 ± 16 years). Before contrast-enhanced imaging, bilateral DWI with b = 0 and 850 s/mm(2) was performed in 2:56 min (3 T) and 3:48 min (7 T), using readout-segmented echo planar imaging (rs-EPI) with a 1.4 × 1.4 mm(2) (3 T)/0.9 × 0.9 mm(2) (7 T) in-plane resolution. Apparent diffusion coefficients (ADC), signal-to-noise (SNR) and contrast-to-noise ratios (CNR) were assessed.

resultsTwenty-eight lesions were detected (18 malignant, 10 benign). CNR and SNR were comparable at both field strengths (p > 0.3). Mean ADC values at 7 T were 4-22% lower than at 3 T (p ≤ 0.03). An ADC threshold of 1.275 × 10(-3) mm(2)/s resulted in a diagnostic specificity of 90% at both field strengths. The sensitivity was 94% and 100% at 3 T and 7 T, respectively.

conclusion7-T DWI of the breast can be performed with 2.4-fold higher spatial resolution than 3 T, without significant differences in SNR if compared to 3 T. KEY POINTS: • 7 T provides a 2.4-fold higher resolution in breast DWI than 3 T • 7 T DWI has a high diagnostic accuracy comparable to that at 3 T • At 7 T malignant lesions had 22 % lower ADC than at 3 T (p < 0.001).

Indexed as

AdultAgedAged, 80 and overBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingDiffusion Magnetic Resonance ImagingEcho-Planar ImagingFemaleFibroadenomaHumansImage EnhancementMastitisMiddle AgedReproducibility of ResultsSensitivity and Specificity7 TeslaBreast cancerBreast MRIDiffusionDWI

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.