Evidence map›Paper›PMID 26310397›Full record

ArticleBMJ open2015

Changes in cardiovascular health score and atherosclerosis progression in middle-aged and older persons in China: a cohort study.

Jingsheng Gao, Minghui Bao, Yan Liu, Jihong Shi, Zhe Huang, Aijun Xing, Yang Wang, Shasha An, Jun Cai, Shouling Wu and 1 more

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingsheng GaoDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Minghui BaoDepartment of Cardiology, Chaoyang Hospital, Capital Medical University, Beijing, China.
Yan LiuDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Jihong ShiDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Zhe HuangDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Aijun XingDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Yang WangDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Shasha AnDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Jun CaiDepartment of Cardiology, Chaoyang Hospital, Capital Medical University, Beijing, China.
Shouling WuDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Xinchun YangDepartment of Cardiology, Chaoyang Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe American Heart Association (AHA) proposed a definition of 4 cardiovascular health behaviours and 3 health factors. On the basis of the 7 metrics, the cardiovascular health score (CHS) was used to estimate individual-level changes in cardiovascular health status. The aim of this study was to investigate whether changes in CHS (⊿CHS) at different time-points are associated with atherosclerosis progression in middle-aged and older persons.

designProspective cohort study in China. SETTINGS: We defined 8 groups (≤-4, -3, -2, -1, 0, 1, 2 and ≥ 3) according to ⊿CHS. The impact of ⊿CHS on the change of brachial-ankle pulse wave velocity (⊿baPWV) and atherosclerosis progression was analysed.

participantsA total of 3951 individuals met the inclusion criteria (≥ 40 years old; no history of stroke, transient ischaemic attack or myocardial infarction) and had complete information.

results⊿baPWV decreased gradually (126.46 ± 355.91, 78.4 ± 343.81, 69.6 ± 316.27, 49.59 ± 287.57, 57.07 ± 261.17, 40.45 ± 264.27, 37.45 ± 283.26 and 21.66 ± 264.17 cm/s, respectively) with increasing ⊿CHS (p for trend<0.05). Multivariate linear regression analysis suggested a negative relationship between these 2 variables, which persisted after adjustment for other risk factors. Each increase in CHS was associated with a reduced baPWV for 15.22 cm/s (B value -15.22, p<0.001).

conclusions⊿CHS were negatively related to ⊿baPWV, which proved to be an independent predictor of the progression of atherosclerosis in middle-aged and older persons. TRIAL REGISTRATION NUMBER: Kailuan study (ChiCTR-TNC-11001489).

Indexed as

Ankle Brachial IndexAtherosclerosisBlood PressureHealth BehaviorHealth StatusPulsatile FlowPulse Wave AnalysisAdultAnkleArmCardiovascular DiseasesChinaDisease ProgressionFemaleHumansMaleCARDIOLOGY

Identifiers

PMID26310397
PMCPMC4554904

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.