Evidence map›Paper›PMID 26309792›Full record

ArticleBioResearch open access2015

Serum Albumin Concentrations in a Multi-Ethnic Cohort of Patients with Human Immunodeficiency Virus Infection from South East London.

James Jy Chong, Ellen Fragaszy, Oliver Dukes, John Cason, Zisis Kozlakidis

Abstract read
In one paragraph

Article in BioResearch open access, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trends and Adaptive Optimal Set Points of CD4AIDS research and treatment · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James Jy ChongKing's College London, School of Medicine , Guy's Campus, Guy's Hospital, Great Maze Pond, London, United Kingdom .
Ellen FragaszyUniversity College London , Institute of Health Informatics and the Farr Institute of Health Informatics Research, London, United Kingdom .
Oliver DukesUniversity College London , Institute of Health Informatics and the Farr Institute of Health Informatics Research, London, United Kingdom .
John CasonKing's College London, School of Medicine , Guy's Campus, Guy's Hospital, Great Maze Pond, London, United Kingdom .
Zisis KozlakidisUniversity College London , Infection and Immunity and the Farr Institute of Health Informatics Research, London, United Kingdom .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human albumin is the most abundant protein in sera and a valuable biomarker in monitoring a variety of diseases. In this study we investigated the relationship between serum albumin concentrations and effects of initiation of highly active antiretroviral therapy (HAART). Serum albumin concentrations amongst 70 HIV-infected patients from diverse ethnicities were analyzed, in the absence of any other confounding comorbidities, over a period of 8 years in South East London, United Kingdom. Serum albumin data was collected, on average, every 4-6 weeks during routine visits. Serum albumin was measured prior to starting HAART, and measured at the first clinic visit after commencing HAART. These were compared to a control group of untreated individuals. Based on our analyses we conclude that serum albumin concentrations increase significantly after the initiation of therapy.

Indexed as

biomarkersHIVvirology

Identifiers

PMID26309792
PMCPMC4497629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.