ArticleBiomedical optics express2015
Investigation of temperature effect on cell mechanics by optofluidic microchips.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Review
- Climate change and women's cancer in the MENA region: assessing temperature-related health impacts.Frontiers in public health · 2025Article
- Cell mechanical properties of human breast carcinoma cells depend on temperature.Scientific reports · 2021Article
- Dielectrophoretic behaviours of microdroplet sandwiched between LN substrates.Scientific reports · 2016Article
- A Comprehensive Review of Optical Stretcher for Cell Mechanical Characterization at Single-Cell Level.Micromachines · 2016Review
- A comprehensive strategy for the analysis of acoustic compressibility and optical deformability on single cells.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here we present the results of a study concerning the effect of temperature on cell mechanical properties. Two different optofluidic microchips with external temperature control are used to investigate the temperature-induced changes of highly metastatic human melanoma cells (A375MC2) in the range of ~0 - 35 °C. By means of an integrated optical stretcher, we observe that cells' optical deformability is strongly enhanced by increasing cell and buffer-fluid temperature. This finding is supported by the results obtained from a second device, which probes the cells' ability to be squeezed through a constriction. Measured data demonstrate a marked dependence of cell mechanical properties on temperature, thus highlighting the importance of including a proper temperature-control system in the experimental apparatus.
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