ArticleInternational journal of clinical and experimental medicine2015
Relationship between peripheral blood dopamine level and internet addiction disorder in adolescents: a pilot study.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 50 citations in OpenAlex.
- Effects of transcranial direct current stimulation and mirror therapy on mental health and dopamine level among spastic quadriplegic cerebral palsy children.BMC pediatrics · 2025Trial
- Potential diagnostic markers of olanzapine efficiency for acute psychosis: a focus on peripheral biogenic amines.BMC psychiatry · 2017Trial
- Electrochemical Sensing of Dopamine with a Nafion-Coated Reduced Graphene Oxide/Polypyrrole-Functionalized Magnetic Nanoparticles Composite.Micromachines · 2026Article
- Adolescent Insomnia Disorder - Problematic Internet Use Nexus: A Convergent Developmental Trajectory - Bridging Neuroimaging Biomarkers, Molecular Susceptibility, and Environmental-Neurocognitive Cascades.Psychology research and behavior management · 2026Review
- Depressive and mobile phone addiction symptoms in Chinese adolescents with major depressive disorder: the mediating effect of alexithymia.BMC psychiatry · 2025Article
- Physical activity moderates the mediating role of depression between experiential avoidance and Internet addiction.Scientific reports · 2025Article
- The relationship between autism spectrum disorder and screen time in children: a literature review.Annals of medicine and surgery (2012) · 2025Review
- Eleven-Year Trajectories of Internet Usage Time and Depression Scores Among Middle-Aged and Older Adults in China: Latent Class Mixed Model Analysis.Journal of medical Internet research · 2025Article
- Computer and Internet Use Among Children and Adolescents in Greece: Levels of Addiction.Cureus · 2024Article
- Clinical Manifestations' Spectrum of Smartphone Addiction: Moving from an Addiction toward a Clinical Syndrome.Clinical practice and epidemiology in mental health : CP & EMH · 2024Article
- Genetic polymorphism in HTR2A rs6313 is associated with internet addiction disorder.Frontiers in psychiatry · 2024Article
- Review
- Association between socioeconomic status and Parkinson's disease: findings from a large incident case-control study.BMJ neurology open · 2023Article
- Digital Addiction and Sleep.International journal of environmental research and public health · 2022Review
- Association between Self-Perceived Periodic Limb Movement during Sleep and Excessive Daytime Sleepiness Depend on Restless Leg Symptoms in Korean Adolescents.International journal of environmental research and public health · 2022Article
- The modulation of mRNA levels of MAOA by electroacupuncture and psychotherapy in patients with pathological internet use.Frontiers in psychiatry · 2022Article
- Biochemical Correlates of Video Game Use: From Physiology to Pathology. A Narrative Review.Life (Basel, Switzerland) · 2021Review
- Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms.Cancers · 2021Article
- mRNA Levels of MAOA and 5-HTFrontiers in psychiatry · 2021Article
- Monoamine and genome-wide DNA methylation investigation in behavioral addiction.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore the association between peripheral blood dopamine level and internet addiction disorder (IAD) in adolescents, this could be used to explain the neurobiological mechanism of Internet addiction disorder.
methods33 adolescents with IAD diagnosed by Young's Internet Addiction Test (IAT) and 33 healthy controls matched by gender and age were investigated in the present study. Peripheral blood dopamine levels of the all subjects were determined by Enzyme Linked Immunosorbent Assay (ELISA).
resultsThe difference of peripheral blood dopamine level between adolescents with IAD and their controls had reached significant level (t = 2.722, P < 0.05). Furthermore, the plasma dopamine level was significantly correlated with the Internet Addiction Test score (r = 0.457, P < 0.001). The result of rank correlation analysis showed a significant positive correlation between the plasma dopamine level and the weekly online time (r = 0.380, P < 0.01) and there was no significant correlation between the duration of Internet use and the plasma dopamine level (r = 0.222, P > 0.05). Binary logistic regression analysis showed that DA level and weekly online time were significant variables which contribute to internet addiction.
conclusionsThe peripheral blood dopamine level is associated with adolescents' internet addiction. The present study provided new evidence in favor of the hypothesis that dopamine played an important role in IAD.
Indexed as
Identifiers
26309680PMC4538113W2399244822What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.