ArticleResearch in autism spectrum disorders2015
Synergic effect of GSTP1 and blood manganese concentrations in Autism Spectrum Disorder.
Abstract read
In one paragraph
Article in Research in autism spectrum disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Assessment of Essential and Toxic Element Levels in the Toenails of Children with Autism Spectrum Disorder.Biological trace element research · 2025Article
- Prenatal Nutritional Factors and Neurodevelopmental Disorders: A Narrative Review.Life (Basel, Switzerland) · 2024Review
- Manganese in autism spectrum disorder and attention deficit hyperactivity disorder: The state of the art.Current research in toxicology · 2024Review
- Consequences of Disturbing Manganese Homeostasis.International journal of molecular sciences · 2023Review
- Are There Sex Differences in Interactive Associations of Environmental Exposure to Lead (Pb), Mercury (Hg), and Manganese (Mn) with GST Genes (Research in autism spectrum disorders · 2023Article
- Trace Element Changes in the Plasma of Autism Spectrum Disorder Children and the Positive Correlation Between Chromium and Vanadium.Biological trace element research · 2022Article
- Research into the Association of Cadmium and Manganese Excretion with Thyroid Function and Behavioral Areas in Adolescents with Autism Spectrum Disorders.Journal of clinical medicine · 2022Article
- Concentrations of Lead, Mercury, Arsenic, Cadmium, Manganese, and Aluminum in the Blood of Pakistani Children with and without Autism Spectrum Disorder and Their Associated Factors.International journal of environmental research and public health · 2021Article
- Interaction of Blood Manganese Concentrations with GSTT1 in Relation to Autism Spectrum Disorder in Jamaican Children.Journal of autism and developmental disorders · 2021Article
- Associations of Metabolic Genes (International journal of environmental research and public health · 2021Article
- Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposure and autism.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2020Review
- Interaction between a Mixture of Heavy Metals (Lead, Mercury, Arsenic, Cadmium, Manganese, Aluminum) andResearch in autism spectrum disorders · 2020Article
- Concentrations of Lead, Mercury, Arsenic, Cadmium, Manganese, and Aluminum in Blood of Romanian Children Suspected of Having Autism Spectrum Disorder.International journal of environmental research and public health · 2019Article
- Interaction of glutathione S-transferase polymorphisms and tobacco smoking during pregnancy in susceptibility to autism spectrum disorders.Scientific reports · 2019Article
- Autism Spectrum Disorders and Perinatal Complications-Is Oxidative Stress the Connection?Frontiers in psychiatry · 2019Article
- Interaction between manganese andResearch in autism spectrum disorders · 2018Article
- Assessment of gender and age effects on serum and hair trace element levels in children with autism spectrum disorder.Metabolic brain disease · 2017Article
- Impaired Redox Control in Autism Spectrum Disorders: Could It Be the X in GxE?Current psychiatry reports · 2017Review
- Role of Metabolic Genes in Blood Aluminum Concentrations of Jamaican Children with and without Autism Spectrum Disorder.International journal of environmental research and public health · 2016Article
- Selection of Suitable Reference Genes for Analysis of Salivary Transcriptome in Non-Syndromic Autistic Male Children.International journal of molecular sciences · 2016Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Mohammad H RahbarDivision of Epidemiology, Human Genetics, and Environmental Sciences (EHGES), University of Texas School of Public Health at Houston, Houston, TX 77030, USA ; Division of Clinical and Translational Sciences, Department of Internal Medicine, Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030,USA ; Biostatistics/Epidemiology/Research Design (BERD) Component, Center for Clinical and Translational Sciences (CCTS), University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Maureen Samms-VaughanDepartment of Child & Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
Jianzhong MaHuman Genetics Center, University of Texas School of Public Health at Houston, Houston, TX 77030, USA.
Jan BresslerDivision of Epidemiology, Human Genetics, and Environmental Sciences (EHGES), University of Texas School of Public Health at Houston, Houston, TX 77030, USA ; Human Genetics Center, University of Texas School of Public Health at Houston, Houston, TX 77030, USA.
Aisha S DickersonBiostatistics/Epidemiology/Research Design (BERD) Component, Center for Clinical and Translational Sciences (CCTS), University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Manouchehr HessabiBiostatistics/Epidemiology/Research Design (BERD) Component, Center for Clinical and Translational Sciences (CCTS), University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Katherine A LovelandDepartment of Psychiatry and Behavioral Sciences, University of Texas Medical School at Houston, Houston, TX 77054, USA.
Megan L GroveHuman Genetics Center, University of Texas School of Public Health at Houston, Houston, TX 77030, USA.
Sydonnie Shakespeare-PellingtonDepartment of Child & Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
Compton BeecherDepartment of Basic Medical Sciences, The University of the West Indies, Mona Campus, Kingston, Jamaica.
Wayne McLaughlinDepartment of Basic Medical Sciences, The University of the West Indies, Mona Campus, Kingston, Jamaica ; Caribbean Genetics (CARIGEN), The University of the West Indies, Mona Campus, Kingston, Jamaica.
Eric BoerwinkleDivision of Epidemiology, Human Genetics, and Environmental Sciences (EHGES), University of Texas School of Public Health at Houston, Houston, TX 77030, USA ; Human Genetics Center, University of Texas School of Public Health at Houston, Houston, TX 77030, USA.
The University of Texas Health Science Center at Houston · USUniversity of the West Indies · JMUniversity of the West Indies System · JM
Funding
U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9MCenter for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4MEpidemiological Research on Autism in Jamaica - Phase IIR01ES022165 · NIEHS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RAHBAR, MOHAMMAD HOSSEIN · 2013 to 2018
$2.8MEpidemiological Research on Autism in JamaicaR21HD057808 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RAHBAR, MOHAMMAD HOSSEIN · 2009 to 2010
$278kNCATS NIH HHS UL1 TR000371NCRR NIH HHS UL1 RR024148NICHD NIH HHS R21 HD057808NIEHS NIH HHS R01 ES022165
Abstract
We used data from 100 age- and sex-matched case-control pairs (age 2-8 years) from Jamaica to investigate whether there is an interaction between glutathione-S-transferase (GST) genes and blood manganese concentrations (BMC) in relation to Autism Spectrum Disorder (ASD). Our findings, indicate that among children who had the Ile/Ile genotype for GST pi 1 (
Indexed as
Autism Spectrum Disorder (ASD)Glutathione S-transferase (GST) genesInteractionsJamaicaManganeseOxidative stress
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.