ArticleeLife2015
Phase-amplitude coupling supports phase coding in human ECoG.
Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed.
- Rhythmic stimulation elicits multiple, concurrent neural responses.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Phase-tuned modulation during reward expectancy in human anterior insular cortex.Communications biology · 2026Article
- Human neuronal firing varies with the frequency of local field potential oscillations.PLoS biology · 2026Article
- Article
- Mapping Executive Function Performance Based on Resting-State EEG in Healthy Individuals: A Systematic and Mechanistic Review.Journal of clinical medicine · 2026Review
- Human neuronal firing is modulated by the frequency of local field potential oscillations.bioRxiv : the preprint server for biology · 2025Article
- Hypomyelination in autism-associated neuroligin-3 mutant mice impairs parvalbumin interneuron excitability, gamma oscillations, and sensory discrimination.Nature communications · 2025Article
- Cortical signatures linked to behavior quantitatively track arousal levels.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Electroencephalography Biomarkers of α5-GABA Positive Allosteric Modulators in Rodents.Biological psychiatry global open science · 2025Article
- Context familiarity is a third kind of episodic memory distinct from item familiarity and recollection.iScience · 2024Article
- Trained recurrent neural networks develop phase-locked limit cycles in a working memory task.PLoS computational biology · 2024Article
- Article
- Review
- Decreased phase information transfer from the mPFC to the BLA: During exploratory behavior in CUMS rats.Frontiers in neuroscience · 2023Article
- When the Whole Is Less Than the Sum of Its Parts: Maximum Object Category Information and Behavioral Prediction in Multiscale Activation Patterns.Frontiers in neuroscience · 2022Article
- An oscillatory pipelining mechanism supporting previewing during visual exploration and reading.Trends in cognitive sciences · 2021Review
- Article
- The what and when of olfactory working memory in humans.Current biology : CB · 2021Article
- Article
- Objective interictal electrophysiology biomarkers optimize prediction of epilepsy surgery outcome.Brain communications · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prior studies have shown that high-frequency activity (HFA) is modulated by the phase of low-frequency activity. This phenomenon of phase-amplitude coupling (PAC) is often interpreted as reflecting phase coding of neural representations, although evidence for this link is still lacking in humans. Here, we show that PAC indeed supports phase-dependent stimulus representations for categories. Six patients with medication-resistant epilepsy viewed images of faces, tools, houses, and scenes during simultaneous acquisition of intracranial recordings. Analyzing 167 electrodes, we observed PAC at 43% of electrodes. Further inspection of PAC revealed that category specific HFA modulations occurred at different phases and frequencies of the underlying low-frequency rhythm, permitting decoding of categorical information using the phase at which HFA events occurred. These results provide evidence for categorical phase-coded neural representations and are the first to show that PAC coincides with phase-dependent coding in the human brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.