Evidence map›Paper›PMID 26308335›Full record

SynthesisPloS one2015

The Uptake of Prevention of Mother-to-Child HIV Transmission Programs in China: A Systematic Review and Meta-Analysis.

Zhaohui Huang, Meihua Jin, Huan Zhou, Zhengquan Dong, Sichao Zhang, Jiankang Han, Keqin Fu, Jianli Wu, Shudong Wu, Huarong Du and 1 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Zhaohui HuangAnhui Provincial Family Planning Institute of Science and Technology, Hefei 230031, Anhui Province, China.
Meihua JinHuzhou Center for Disease Control and Prevention, Huzhou 313000, Zhejiang Province, China.
Huan ZhouHealth management teaching and research section, the first affiliated hospital of Bengbu medical college, Bengbu, Anhui 233000, P.R. China.
Zhengquan DongHuzhou Center for Disease Control and Prevention, Huzhou 313000, Zhejiang Province, China.
Sichao ZhangHuzhou Center for Disease Control and Prevention, Huzhou 313000, Zhejiang Province, China.
Jiankang HanHuzhou Center for Disease Control and Prevention, Huzhou 313000, Zhejiang Province, China.
Keqin FuAnhui Provincial Family Planning Institute of Science and Technology, Hefei 230031, Anhui Province, China.
Jianli WuAnhui Provincial Family Planning Institute of Science and Technology, Hefei 230031, Anhui Province, China.
Shudong WuAnhui Provincial Family Planning Institute of Science and Technology, Hefei 230031, Anhui Province, China.
Huarong DuAnhui Provincial Family Planning Institute of Science and Technology, Hefei 230031, Anhui Province, China.
Zhongrong YangHuzhou Center for Disease Control and Prevention, Huzhou 313000, Zhejiang Province, China.
Huzhou University · CNJiangsu Provincial Family Planning Institute of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNo systematic review of prevention of mother to child transmission (PMTCT) in China has been performed. We aimed to estimate the uptake of PMTCT programs services in China.

methodsWe searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, and Wanfang (Chinese) to identify research studies. Only descriptive epidemiological studies were eligible for this study.

resultsA total of 57 eligible cross-section studies were finally included. We estimated that the mean HIV-positive rate of exposed infants was 4.4% (95% CI = 3.2-5.5), and more than 33% of exposed infants had not undergone HIV diagnostic testing. The percentage of initiating antiretroviral therapy (ART) in HIV-positive women was 71.0% (95% CI = 66.3-75.8), and that for initiating antiretroviral prophylaxis (ARP) in exposed infants was 78.3% (95% CI = 74.9-81.8); also, 31.3% (95% CI = 15.5-47.0) of women with HIV and < 1% of exposed infants received the combination of three antiretroviral drugs. There were bigger gap of uptake of PMTCT programs between income levels, and cities with a low income level had a higher percentage of initiating ART in HIV-positive women (80%) and ARP in exposed infants (85%) compared to cities with high-middle income (57% and 65%, respectively) (P<0.05).

conclusionsThis paper highlights the need to further scale up PMTCT services in China, especially in regions with the lowest coverage, so that more women can access and utilize them. However, some estimated outcome should be interpreted with caution due to the high level of heterogeneity and the small number of studies.

Indexed as

MothersChinaHIV InfectionsHumansInfectious Disease Transmission, VerticalOutcome Assessment, Health CarePatient Acceptance of Health Care

Identifiers

PMID26308335
PMCPMC4550389
OpenAlexW2110159207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.