Evidence map›Paper›PMID 26308062›Full record

ReviewPathogens (Basel, Switzerland)2015

Systems Level Dissection of Candida Recognition by Dectins: A Matter of Fungal Morphology and Site of Infection.

Lisa Rizzetto, Tobias Weil, Duccio Cavalieri

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Plants (Basel, Switzerland) · 2025
    Review
  3. Filament Negative RegulatorJournal of fungi (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Antifungal Immunological Defenses in Newborns.Frontiers in immunology · 2017
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lisa RizzettoResearch and Innovation Center, Fondazione E. Mach, via E. Mach 1, San Michele all'Adige (TN) 38010, Italy. lisa.rizzetto@fmach.it.
Tobias WeilResearch and Innovation Center, Fondazione E. Mach, via E. Mach 1, San Michele all'Adige (TN) 38010, Italy. tobias.weil@fmach.it.
Duccio CavalieriResearch and Innovation Center, Fondazione E. Mach, via E. Mach 1, San Michele all'Adige (TN) 38010, Italy. duccio.cavalieri@fmach.it.
Fondazione Edmund Mach · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida albicans is an ubiquitous fungal commensal of human skin and mucosal surfaces, and at the same time a major life-threatening human fungal pathogen in immunocompromised individuals. Host defense mechanisms rely on the capacity of professional phagocytes to recognize Candida cell wall antigens. During the past decade, the host immune response to Candida was dissected in depth, highlighting the essential role of C-type lectin receptors, especially regarding the power of the Dectins' family in discriminating between the tolerated yeast-like form of Candida and its invading counterpart, the hyphae. This review focuses on the immuno-modulatory properties of the Candida morphologies and their specific interactions with the host innate immune system in different body surfaces.

Indexed as

Candida albicansC-type lectin receptorsinnate immunitymorphologypathogenyeast-hyphae

Identifiers

PMID26308062
PMCPMC4584279
OpenAlexW2101984662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.