ArticleLife (Basel, Switzerland)2015
The Effects of Temperature and Growth Phase on the Lipidomes of Sulfolobus islandicus and Sulfolobus tokodaii.
Article in Life (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Comparative microbial lipidomics: structural diversity, adaptive strategies, and analytical advances.Folia microbiologica · 2026Review
- Novel Extended Tetraether Lipids Found in a High-COEnvironmental microbiology · 2026Article
- Cyclization of archaeal membrane lipids impacts membrane protein activity and archaellum formation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The Archaeal Cell Cycle.Annual review of cell and developmental biology · 2024Review
- Development of a defined medium for the heterotrophic cultivation of Metallosphaera sedula.Extremophiles : life under extreme conditions · 2024Article
- Identification of two archaeal GDGT lipid-modifying proteins reveals diverse microbes capable of GMGT biosynthesis and modification.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Tetraether archaeal lipids promote long-term survival in extreme conditions.Molecular microbiology · 2024Article
- Mode of carbon and energy metabolism shifts lipid composition in the thermoacidophileApplied and environmental microbiology · 2024Article
- Unraveling the multiplicity of geranylgeranyl reductases in Archaea: potential roles in saturation of terpenoids.Extremophiles : life under extreme conditions · 2024Review
- Membrane Adaptations and Cellular Responses ofInternational journal of molecular sciences · 2023Article
- Membrane lipid and expression responses ofFrontiers in microbiology · 2023Article
- The catalytic and structural basis of archaeal glycerophospholipid biosynthesis.Extremophiles : life under extreme conditions · 2022Review
- First Isolation and Structure Elucidation of GDNT-β-Glu - Tetraether Lipid Fragment from Archaeal Sulfolobus Strains.ChemistryOpen · 2021Article
- The Cell Membrane ofInternational journal of molecular sciences · 2020Review
- The influence of the specific growth rate on the lipid composition of Sulfolobus acidocaldarius.Extremophiles : life under extreme conditions · 2020Article
- Gene deletions leading to a reduction in the number of cyclopentane rings in Sulfolobus acidocaldarius tetraether lipids.FEMS microbiology letters · 2018Article
- Heat Stress Dictates Microbial Lipid Composition along a Thermal Gradient in Marine Sediments.Frontiers in microbiology · 2017Article
- Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics.International journal of molecular sciences · 2016Review
- Influence of Growth Phase, pH, and Temperature on the Abundance and Composition of Tetraether Lipids in the Thermoacidophile Picrophilus torridus.Frontiers in microbiology · 2016Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The functionality of the plasma membrane is essential for all organisms. Adaption to high growth temperatures imposes challenges and Bacteria, Eukarya, and Archaea have developed several mechanisms to cope with these. Hyperthermophilic archaea have earlier been shown to synthesize tetraether membrane lipids with an increased number of cyclopentane moieties at higher growth temperatures. Here we used shotgun lipidomics to study this effect as well as the influence of growth phase on the lipidomes of Sulfolobus islandicus and Sulfolobus tokodaii for the first time. Both species were cultivated at three different temperatures, with samples withdrawn during lag, exponential, and stationary phases. Three abundant tetraether lipid classes and one diether lipid class were monitored. Beside the expected increase in the number of cyclopentane moieties with higher temperature in both archaea, we observed previously unreported changes in the average cyclization of the membrane lipids throughout growth. The average number of cyclopentane moieties showed a significant dip in exponential phase, an observation that might help to resolve the currently debated biosynthesis pathway of tetraether lipids.
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