Evidence map›Paper›PMID 26308023›Full record

ArticleInternational journal of environmental research and public health2015

An Investigation of Organic and Inorganic Mercury Exposure and Blood Pressure in a Small-Scale Gold Mining Community in Ghana.

Mozhgon Rajaee, Brisa N Sánchez, Elisha P Renne, Niladri Basu

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Vascular Dysfunction Induced by Mercury Exposure.International journal of molecular sciences · 2019
    Review
  13. Article
  14. Article
  15. The aging kidney and the nephrotoxic effects of mercury.Journal of toxicology and environmental health. Part B, Critical reviews · 2017
    Review
  16. Article
  17. An Integrated Assessment Approach to Address Artisanal and Small-Scale Gold Mining in Ghana.International journal of environmental research and public health · 2015
    Article
  18. Integrated assessment of artisanal and small-scale gold mining in Ghana--part 1: human health review.International journal of environmental research and public health · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mozhgon RajaeeDepartment of Environmental Health Sciences, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA. mrajae@umich.edu.
Brisa N SánchezDepartment of Biostatistics, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA. brisa@umich.edu.
Elisha P RenneDepartment of Anthropology, University of Michigan, 101 West Hall, Ann Arbor, MI 48109, USA. erenne@umich.edu.
Niladri BasuDepartment of Environmental Health Sciences, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA. niladri.basu@mcgill.ca.

Funding

University of Michigan Minority Health and Health Disparities International Research Training ProgramT37MD001425 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOULTON, MATTHEW LESTER · 2005 to 2025
$4.8M
NIMHD NIH HHS T37 MD001425NIMHD NIH HHS T37 MD001425-15
6 · The paper itself

Abstract

There is increasing concern about the cardiovascular effects of mercury (Hg) exposure, and that organic methylmercury and inorganic Hg(2+) may affect the cardiovascular system and blood pressure differentially. In small-scale gold mining communities where inorganic, elemental Hg exposures are high, little is known about the effects of Hg on blood pressure. In 2011, we assessed the relationship between Hg exposure and blood pressure (BP) in a cross-sectional study of adults from a small-scale gold mining community, Kejetia, and subsistence farming community, Gorogo, in Ghana's Upper East Region. Participants' resting heart rate and BP were measured, and hair and urine samples were provided to serve as biomarkers of organic and inorganic Hg exposure, respectively. Participants included 70 miners and 26 non-miners from Kejetia and 75 non-miners from Gorogo. Total specific gravity-adjusted urinary and hair Hg was higher among Kejetia miners than Kejetia non-miners and Gorogo participants (median urinary Hg: 5.17, 1.18, and 0.154 µg/L, respectively; hair Hg: 0.945, 0.419, and 0.181 µg/g, respectively). Hypertension was prevalent in 17.7% of Kejetia and 21.3% of Gorogo participants. Urinary and hair Hg were not significantly associated with systolic or diastolic BP for Kejetia or Gorogo participants while adjusting for sex, age, and smoking status. Although our results follow trends seen in other studies, the associations were not of statistical significance. Given the unique study population and high exposures to inorganic Hg, the work contained here will help increase our understanding of the cardiovascular effects of Hg.

Indexed as

MinersOccupational ExposureAdultAgedBiomarkersBlood PressureCross-Sectional StudiesFemaleGhanaGoldHairHeart RateHumansMaleMercuryMiddle AgedBiomarkersGoldMercuryartisanal and small-scale gold miningASGMblood pressureGhanamercury

Identifiers

PMID26308023
PMCPMC4555326

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.