ArticleInternational journal of molecular sciences2015
Atherosclerotic Calcification Detection: A Comparative Study of Carotid Ultrasound and Cone Beam CT.
Article in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- [A comparative study of color Doppler ultrasound and CT angiography for preoperative evaluation of perforator vessels in free posterior interosseous artery flap].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Article
- Calcification detection on upper extremity arteries: a comparison of ultrasonic and X-ray methods.PeerJ · 2023Article
- High systemic immune-inflammation index is associated with carotid plaque vulnerability: New findings based on carotid ultrasound imaging in patients with acute ischemic stroke.Frontiers in neurology · 2022Article
- Ultrasound Methods in the Evaluation of Atherosclerosis: From Pathophysiology to Clinic.Biomedicines · 2021Review
- Assessment of relationship between extracranial and intracranial carotid calcifications-a retrospective cone beam computed tomography study.Dento maxillo facial radiology · 2019Article
- Hydroxyapatite-binding micelles for the detection of vascular calcification in atherosclerosis.Journal of materials chemistry. B · 2019Article
- Carotid plaque composition by CT angiography in asymptomatic subjects: a head-to-head comparison to ultrasound.European radiology · 2019Article
- Performance of acoustic radiation force impulse ultrasound imaging for carotid plaque characterization with histologic validation.Journal of vascular surgery · 2017Article
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9 authors.
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Abstract
BACKGROUND AND
aimArterial calcification is often detected on ultrasound examination but its diagnostic accuracy is not well validated. The aim of this study was to determine the accuracy of carotid ultrasound B mode findings in detecting atherosclerotic calcification quantified by cone beam computed tomography (CBCT).
methodsWe analyzed 94 carotid arteries, from 88 patients (mean age 70 ± 7 years, 33% females), who underwent pre-endarterectomy ultrasound examination. Plaques with high echogenic nodules and posterior shadowing were considered calcified. After surgery, the excised plaques were examined using CBCT, from which the calcification volume (mm3) was calculated. In cases with multiple calcifications the largest calcification nodule volume was used to represent the plaque. Carotid artery calcification by the two imaging techniques was compared using conventional correlations.
resultsCarotid ultrasound was highly accurate in detecting the presence of calcification; with a sensitivity of 88.2%. Based on the quartile ranges of calcification volumes measured by CBCT we have divided plaque calcification into four groups: <8; 8-35; 36-70 and >70 mm3. Calcification volumes ≥8 were accurately detectable by ultrasound with a sensitivity of 96%. Of the 21 plaques with <8 mm3 calcification volume; only 13 were detected by ultrasound; resulting in a sensitivity of 62%. There was no difference in the volume of calcification between symptomatic and asymptomatic patients.
conclusionCarotid ultrasound is highly accurate in detecting the presence of calcified atherosclerotic lesions of volume ≥8 mm3; but less accurate in detecting smaller volume calcified plaques. Further development of ultrasound techniques should allow better detection of early arterial calcification.
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