ArticleMolecules (Basel, Switzerland)2015
Ultrasound-Assisted Aqueous Two-Phase System for Extraction and Enrichment of Zanthoxylum armatum Lignans.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 39 citations in OpenAlex.
- Optimal extraction conditions and quantification of lignan phytoestrogens in cereal grains using targeted LC-MS/MS.Frontiers in nutrition · 2024Article
- Biological Potential and Therapeutic Effectiveness of Phytoproduct 'Fargesin' in Medicine: Focus on the Potential of an Active Phytochemical ofRecent advances in inflammation & allergy drug discovery · 2024Review
- Extraction Systems and Analytical Techniques for Food Phenolic Compounds: A Review.Foods (Basel, Switzerland) · 2022Review
- Optimized Ultrasound-Assisted Extraction of Lignans fromMolecules (Basel, Switzerland) · 2022Article
- Ecofriendly application of coconut coir (Cocos nucifera) extract for silk dyeing.Environmental science and pollution research international · 2022Article
- Tetrahydrofurofuranoid Lignans, Eudesmin, Fargesin, Epimagnolin A, Magnolin, and Yangambin Inhibit UDP-Glucuronosyltransferase 1A1 and 1A3 Activities in Human Liver Microsomes.Pharmaceutics · 2021Article
- A Novel Green Extraction Technique for Extracting Flavonoids fromMaterials (Basel, Switzerland) · 2020Article
- Salting-out extraction of ginsenosides from the enzymatic hydrolysates ofJournal of ginseng research · 2020Article
- An Efficient Approach for Lipase-Catalyzed Synthesis of Retinyl Laurate Nutraceutical by Combining Ultrasound Assistance and Artificial Neural Network Optimization.Molecules (Basel, Switzerland) · 2017Article
- Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes.International journal of molecular sciences · 2017Article
- Highly Efficient Synthesis of an Emerging Lipophilic Antioxidant: 2-Ethylhexyl Ferulate.Molecules (Basel, Switzerland) · 2016Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
In the study, an aqueous two phase system (ATPS) coupled with ultrasound was employed to extract lignans from Zanthoxylum armatum. Three standard lignans, namely (-)-fargesin, sesamin and L-asarinin, were used as marker compounds, and extraction was optimized and projected by response surface methodology (RSM) and artificial neural network (ANN). The optimal condition for ATPS with 20% n-propanol and 24% (NH4)2SO4 coupled with ultrasonic-assisted extraction including a solvent to solid ratio of 15:1, a temperature of 40 °C, and a treatment time of 55 min was obtained. Under the condition, the yield of (-)-fargesin increased 15.12%, and the purities of (-)-fargesin, sesamin and L-asarinin reached 2.222%, 1.066%, and 1.583%, with an increase of 44.38%, 25.70%, and 26.34% compared to those extracted with 95% ethanol, respectively. Coefficient of the determined (0.9855) and mean squared error (0.0018) of ANN model suggested good fitness and generalization of the ANN. Taken together, the results showed that ultrasonic-assisted ATPS can be a suitable method for extraction and enrichment of lignans from Z. armatum.
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