Evidence map›Paper›PMID 26307955›Full record

ArticleMolecules (Basel, Switzerland)2015

A New Ionone Glycoside and Three New Rhemaneolignans from the Roots of Rehmannia glutinosa.

Meng Li, Xiaolan Wang, Xiaoke Zheng, Jianchao Wang, Wei Zhao, Kai Song, Xuan Zhao, Yanli Zhang, Haixue Kuang, Weisheng Feng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Computational and structural biotechnology journal · 2021
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Meng LiSchool of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China. limeng31716@163.com.
Xiaolan WangCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. wxl_@163.com.
Xiaoke ZhengCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. zhengxk.2006@163.com.
Jianchao WangCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. 15238397097@163.com.
Wei ZhaoCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. 18236159652@163.com.
Kai SongCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. songky5901@163.com.
Xuan ZhaoCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. zhengxk.2006@163.com.
Yanli ZhangCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. zyl2013hnzy@163.com.
Haixue KuangSchool of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China. hxkuang@hotmail.com.
Weisheng FengCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. fwsh@hactcm.edu.cn.
Henan University of Traditional Chinese Medicine · CNHeilongjiang University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new ionone glycoside, frehmaglutoside I (1), and three new rhemaneolignans A-C (2-4) were isolated from the 95% EtOH extract of the roots of Rehmannia glutinosa. Their structures were determined by extensive spectroscopic (UV, IR, HR-ESI-MS, 1D and 2D NMR) analyses. In addition, these compounds were evaluated for their protective effects on cardiocytes impaired by doxorubicin in H9c2 cells. Among them, compounds 1-3 exhibited protective effects against DOX-induced cardiotoxicity.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsCell LineDoxorubicinGlycosidesHumansLignansMyocytes, CardiacPlant RootsRehmanniaSpectrum AnalysisDoxorubicinGlycosidesLignansionone glycosideRehmannia glutinosarhemaneolignansthe protective effects of cardiomyocytes

Identifiers

PMID26307955
PMCPMC6332001
OpenAlexW1899418045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.