ArticleJournal of neurovirology2016
Human immunodeficiency virus has similar effects on brain volumetrics and cognition in males and females.
Article in Journal of neurovirology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Sex Differences in Neurocognitive Function in Adults with HIV: Patterns, Predictors, and Mechanisms.Current psychiatry reports · 2019Pooled it
- Resting-state neural signatures of depressive symptoms in acute HIV.Journal of neurovirology · 2020Trial
- The Effect of an HIV Self-Management Intervention on Neurocognitive Behavioral Processing.Western journal of nursing research · 2019Trial
- Brief Report: Low-Dose Hydrocortisone Has Acute Enhancing Effects on Verbal Learning in HIV-Infected Men.Journal of acquired immune deficiency syndromes (1999) · 2017Trial
- Multishell diffusion MRI reveals whole-brain white matter changes in HIV.Human brain mapping · 2023Article
- Chronic brain damage in HIV-infected individuals under antiretroviral therapy is associated with viral reservoirs, sulfatide release, and compromised cell-to-cell communication.Cellular and molecular life sciences : CMLS · 2023Article
- Difference in the neurocognitive functions of WLWH and MLWH in an Italian cohort of people living with HIV.Journal of neurovirology · 2022Article
- Greater Sensorimotor Deficits and Abnormally Lower Globus Pallidus Fractional Anisotropy in HIV+ Women than in HIV+ Men.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021Article
- Neurocognitive Complications of HIV Infection in Women: Insights from the WIHS Cohort.Current topics in behavioral neurosciences · 2021Review
- Sex Differences in the Patterns and Predictors of Cognitive Function in HIV.Frontiers in neurology · 2020Article
- Sex differences in neurocognitive screening among adults living with HIV in China.Journal of neurovirology · 2019Article
- Sex differences in HIV-associated cognitive impairment.AIDS (London, England) · 2018Article
- Cognitive Performance and Frailty in Older HIV-Positive Adults.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Resting-state connectivity and spontaneous activity of ventromedial prefrontal cortex predict depressive symptomology and peripheral inflammation in HIV.Journal of neurovirology · 2018Article
- Differences in Cognitive Function Between Women and Men With HIV.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Cognitive Burden of Common Non-antiretroviral Medications in HIV-Infected Women.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Verbal and spatial working memory among drug-using HIV-infected men and women.Journal of neurovirology · 2018Article
- Effects of HIV Infection, methamphetamine dependence and age on cortical thickness, area and volume.NeuroImage. Clinical · 2018Article
- Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging.Scientific reports · 2017Article
- Sex differences in HIV effects on visual memory among substance-dependent individuals.Journal of clinical and experimental neuropsychology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Most studies that have examined neuropsychological impairments associated with human immunodeficiency virus (HIV) have focused on males, yet females represent one of the largest groups of newly infected patients. Further, few studies have examined neuropsychological performance and neuroimaging outcomes among females compared to males in the modern era of highly active anti-retroviral therapy (HAART). The present study investigated neuropsychological performance and brain volumetrics among HIV+ males (n = 93) and females (n = 44) on stable HAART compared to HIV seronegative (HIV-) males (n = 42) and females (n = 49). Results revealed a significant effect of HIV on neuropsychological performance and neuroimaging measures. An effect of gender, independent of HIV status, was also observed for neuroimaging measures but not neuropsychological performance. Additionally, no significant differences in neuropsychological performance or brain volumetrics were seen between HIV+ males and females. No significant interaction was observed between HIV and gender on either neuropsychological or neuroimaging indices. Our results suggest that both HIV+ males and females treated with HAART experience similar outcomes in terms of brain integrity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.