Evidence map›Paper›PMID 26305992›Full record

Trial reportJournal of palliative medicine2015

An Advanced Practice Nurse Coordinated Multidisciplinary Intervention for Patients with Late-Stage Cancer: A Cluster Randomized Trial.

Ruth McCorkle, Sangchoon Jeon, Elizabeth Ercolano, Mark Lazenby, Amanda Reid, Marianne Davies, Diane Viveiros, Scott Gettinger

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of palliative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  10. Early palliative care for adults with advanced cancer.The Cochrane database of systematic reviews · 2017
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  16. Systematic vs. on-demand early palliative care in gastric cancer patients: a randomized clinical trial assessing patient and healthcare service outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
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  20. Palliative care case management in a surgical department for patients with gastrointestinal cancer-a register-based cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruth McCorkle1 School of Nursing, Yale University , New Haven, Connecticut.
Sangchoon Jeon1 School of Nursing, Yale University , New Haven, Connecticut.
Elizabeth Ercolano1 School of Nursing, Yale University , New Haven, Connecticut.
Mark Lazenby1 School of Nursing, Yale University , New Haven, Connecticut.
Amanda Reid4 Smilow Cancer Hospital at Yale-New Haven , New Haven, Connecticut.
Marianne Davies4 Smilow Cancer Hospital at Yale-New Haven , New Haven, Connecticut.
Diane Viveiros4 Smilow Cancer Hospital at Yale-New Haven , New Haven, Connecticut.
Scott Gettinger5 School of Medicine, Yale University , New Haven, Connecticut.

Funding

An Intervention to Improve Outcomes in Patients with Advanced CancerR01NR011872 · NINR · YALE UNIVERSITY · PI MCCORKLE, RUTH · 2009 to 2011
$1.4M
NINR NIH HHS R01NR011872
6 · The paper itself

Abstract

backgroundEarly palliative care provided through a palliative care consultative service is effective in enhancing patient outcomes. However, it is unknown whether the integration of palliative care as part of routine comprehensive cancer care improves patients' self-reported clinical outcomes.

objectiveThe objective of this study was to evaluate the effects of a multidisciplinary coordinated intervention by advanced practice nurses at the clinic level on outcomes with patients newly diagnosed with late-stage cancer.

methodsA clustered, randomized, controlled trial design was used. Four disease-specific multidisciplinary clinics were randomized to the 10-week intervention (gynecologic and lung clinics) or to enhanced usual care (head and neck and gastrointestinal clinics). Patient primary outcomes (symptoms, health distress, depression, functional status, self-reported health) were collected at baseline and one and three months, and secondary outcomes were collected one and three months postbaseline. General linear mixed model analyses with a covariance structure of within-subject correlation was used to examine the intervention's effect.

resultsThe sample included 146 patients with newly diagnosed late-stage cancers. We found no differences between the two groups on the primary patient-reported outcomes at one and three months postbaseline; however, physical and emotional symptoms remained stable or significantly improved from baseline for both groups. Overall, secondary outcomes remained stable within the groups.

conclusionIn this translational study, we demonstrated that if patients newly diagnosed with late-stage cancer were managed by disease-specific multidisciplinary teams who palliated their symptoms, providing whole-patient care, patient outcomes remained stable or improved.

Indexed as

Advanced Practice NursingAgedCancer Care FacilitiesCluster AnalysisFemaleHumansLeast-Squares AnalysisMaleMiddle AgedNeoplasmsOutcome and Process Assessment, Health CareOutpatient Clinics, HospitalPalliative CarePatient Care TeamQuality of LifeTranslational Research, Biomedical

Identifiers

PMID26305992
PMCPMC4638201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.