Evidence map›Paper›PMID 26305712›Full record

ArticlePediatric blood & cancer2016

Tobacco Use Among Siblings of Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study.

David Buchbinder, Kevin Oeffinger, Conrado Franco-Villalobos, Yutaka Yasui, Melissa A Alderfer, Gregory T Armstrong, Jacqueline Casillas, Jennifer Ford, Kevin R Krull, Wendy Leisenring and 4 more

Abstract read
In one paragraph

Article in Pediatric blood & cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 2 countries.

David BuchbinderDivision of Hematology, Department of Pediatrics, Children's Hospital of Orange County, Orange, California.
Kevin OeffingerMemorial Sloan-Kettering Cancer Center, New York, New York.
Conrado Franco-VillalobosDepartment of Biostatistics, School of Public and Health, University of Alberta, Alberta, Canada.
Yutaka YasuiDepartment of Biostatistics, School of Public and Health, University of Alberta, Alberta, Canada.
Melissa A AlderferCenter for Healthcare Delivery Science, Nemours Children's Health System, Wilmington, Delaware.
Gregory T ArmstrongDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee.
Jacqueline CasillasDavid Geffen School of Medicine at University of California at Los Angeles (UCLA) and UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California.
Jennifer FordMemorial Sloan-Kettering Cancer Center, New York, New York.
Kevin R KrullDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee.
Wendy LeisenringCancer Prevention Program at Fred Hutchinson Cancer Research Center, Seattle, Washington.
Christopher RecklitisPerini Family Survivors' Center, Dana-Farber Cancer Institute, Boston, Massachusetts.
Leslie L RobisonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee.
Lonnie K ZeltzerDavid Geffen School of Medicine at University of California at Los Angeles (UCLA) and UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California.
E Anne LownDepartment of Social and Behavioral Sciences, University of California at San Francisco, San Francisco, California.
St. Jude Children's Research Hospital · USMemorial Sloan Kettering Cancer Center · USUniversity of Alberta · CAChildren's Hospital of Orange County · USDana-Farber Cancer Institute · USFred Hutch Cancer Center · USThomas Jefferson University · USUCLA Jonsson Comprehensive Cancer CenterUniversity of California, Los Angeles · USUniversity of California, San Francisco · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS SupplU24CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Gregory Armstrong · 1999 to 2026
$96.7M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016042NCI NIH HHS U24 CA055727NCI NIH HHS U24CA55727
6 · The paper itself

Abstract

backgroundHaving a brother or sister with childhood cancer may influence health behaviors during adulthood. The aim of this study was to compare tobacco use in siblings of survivors with peers and to identify factors associated with sibling tobacco use. PROCEDURES: A retrospective cohort study was conducted using adult siblings (N = 1,974) of 5+ year cancer survivors in the Childhood Cancer Survivor Study (CCSS) and participants (N = 24,105, weighted to match CCSS) in the 2007 National Health Interview Survey. Self-reported tobacco use, sociodemographic, and cancer-related risk factors were analyzed.

resultsSiblings were equally likely to have ever smoked compared to their peers (odds ratio [OR] 1.02, 95% confidence interval [CI] 0.93-1.12). Siblings were less likely to be current smokers (OR 0.83, 95%CI 0.73-0.94), but more likely to be former smokers (OR 1.21, 95%CI 1.08-1.35). Siblings with low education were more likely to ever smoke (OR 1.51, 95%CI 1.15-2.00) and be current smokers (OR 1.67, 95%CI 1.24-2.26) compared to their peers. Among siblings, risk factors for current tobacco use included the following: low income <$20,000 (OR 1.66, 95%CI 1.09-2.54), low education (OR 6.68, 95%CI 4.07-10.97), psychological distress (OR 5.36, 95%CI 2.21-13.02), and heavy alcohol use (OR 3.68, 95%CI 2.50-5.41).

conclusionsSiblings of survivors take up smoking at similar rates to their peers, but are more likely to quit. Efforts are needed to address disparities by providing greater psychosocial support and education for the lowest socioeconomic status families facing childhood cancer.

Indexed as

Health BehaviorNeoplasmsSurvivorsAdultCohort StudiesFemaleHumansMaleRetrospective StudiesSiblingsSmokingSocioeconomic Factorschildhood cancer survivorshealth behaviorsiblingssmokingtobacco

Identifiers

PMID26305712
PMCPMC4715577
OpenAlexW1585012891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.