Evidence map›Paper›PMID 26304955›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2016

Adopting new gamma cameras and reconstruction algorithms: Do we need to re-establish normal reference values?

Timothy L Miao, Vinay Kansal, R Glenn Wells, Iftikhar Ali, Terrence D Ruddy, Benjamin J W Chow

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. New techniques, distinctive population, unique normal databases.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  5. Myocardial perfusion imaging: Lessons learned and work to be done-update.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Review
  6. Successful innovation: A time for change?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  7. Sources of variability of gated myocardial perfusion SPECT quantitative parameters.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Timothy L MiaoDepartment of Medicine (Cardiology and Nuclear Medicine), University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
Vinay KansalDepartment of Medicine (Cardiology and Nuclear Medicine), University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
R Glenn WellsDepartment of Medicine (Cardiology and Nuclear Medicine), University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
Iftikhar AliDepartment of Medicine (Cardiology and Nuclear Medicine), University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
Terrence D RuddyDepartment of Medicine (Cardiology and Nuclear Medicine), University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
Benjamin J W ChowDepartment of Medicine (Cardiology and Nuclear Medicine), University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada. bchow@ottawaheart.ca.
University of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of adopting new single photon emission computed tomography (SPECT) cameras and new reconstruction algorithms on left ventricular (LV) volumes has not been well established. We sought to understand the impact of hardware and software changes on normal LV reference ranges.

methodsConsecutive patients who underwent stress Tc-99m tetrofosmin 8-frame gated SPECT MPI were screened. Patients with a history of myocardial infarction, coronary revascularization, abnormal MPI, or known LV dysfunction/reduced ejection fraction were excluded. A total of 1953 consecutive normal patients, with rest LV end-diastolic volume (EDV) and end-systolic volume (ESV) measurements were analyzed. After stratifying according to sex, LV volumes indexed to body surface area were compared across the different gamma cameras.

resultsIn a normal population, measurements with CZT were different from those obtained by the dual-headed NaI gamma cameras for LV EDVi (men: 53.6 ± 10.4 vs 48.3 ± 10.2 mL/m(2) and women: 43.3 ± 8.9 vs 37.8 ± 9.3 mL/m(2); P < 0.001) and LV ESVi (men: 21.7 ± 7.0 vs 16.9 ± 6.2 mL/m(2) and women: 13.4 ± 5.3 vs 10.6 ± 4.7 mL/m(2); P < 0.001). Inter- and intra-observer reliability for all measures was excellent. These findings were verified in a prospectively collected cohort. A sub-analysis of LV measurements comparing new resolution recovery and standard reconstruction software revealed no significant differences in LV measures.

conclusionThis study demonstrates that normal references ranges of LV volumes vary between SPECT cameras and confirms the need for establishing reference values that are camera specific.

Indexed as

AlgorithmsGamma CamerasEquipment DesignEquipment Failure AnalysisFemaleHeart VentriclesHumansImage Interpretation, Computer-AssistedMaleMiddle AgedRadionuclide ImagingReference ValuesReproducibility of ResultsSensitivity and SpecificityStroke VolumeVentricular Function, Leftcadmium-zinc-telluridegamma cameraLeft ventricular volumes

Identifiers

PMID26304955
OpenAlexW1192590027

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.