Evidence map›Paper›PMID 26304915›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Mercadeo Virus: A Novel Mosquito-Specific Flavivirus from Panama.

Jean-Paul Carrera, Hilda Guzman, Davis Beltrán, Yamilka Díaz, Sandra López-Vergès, Rolando Torres-Cosme, Vsevolod Popov, Steven G Widen, Thomas G Wood, Scott C Weaver and 3 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jean-Paul CarreraDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Hilda GuzmanDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Davis BeltránDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Yamilka DíazDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Sandra López-VergèsDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Rolando Torres-CosmeDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Vsevolod PopovDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Steven G WidenDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Thomas G WoodDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Scott C WeaverDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Lorenzo Cáceres-CarreraDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Nikos VasilakisDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas.
Robert B TeshDepartment of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine, Columbus University, Panama City, Panama; Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas; Institute for Human Infectious and Immunity, The University of Texas Medical Branch, Galveston, Texas; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas rtesh@utmb.edu.

Funding

NIAID NIH HHS HHSN272201000040I
6 · The paper itself

Abstract

Viruses in the genus Flavivirus (family Flaviviridae) include many arthropod-borne viruses of public health and veterinary importance. However, during the past two decades an explosion of novel insect-specific flaviviruses (ISFs), some closely related to vertebrate pathogens, have been discovered. Although many flavivirus pathogens of vertebrates have been isolated from naturally infected mosquitoes in Panama, ISFs have not previously been reported from the country. This report describes the isolation and characterization of a novel ISF, tentatively named Mercadeo virus (MECDV), obtained from Culex spp. mosquitoes collected in Panama. Two MECDV isolates were sequenced and cluster phylogenetically with cell-fusing agent virus (CFAV) and Nakiwogo virus (NAKV) to form a distinct lineage within the insect-specific group of flaviviruses.

Indexed as

AnimalsBase SequenceCulexFemaleFlavivirusFlavivirus InfectionsHumansInsect VectorsMaleMolecular Sequence DataPanamaPhylogenyRetrospective StudiesSequence Analysis, DNA

Identifiers

PMID26304915
PMCPMC4703282

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.