Evidence map›Paper›PMID 26304561›Full record

SynthesisIndian heart journal

Prevalence, treatments and outcomes of coronary artery disease in Indians: A systematic review.

Mangala Rao, Denis Xavier, Padmini Devi, Alben Sigamani, Atiya Faruqui, Rajeev Gupta, Prafulla Kerkar, Rajendra Kumar Jain, Rajnish Joshi, N Chidambaram and 6 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Bridging the Gap: Addressing Geographic and Socioeconomic Inequities in Access to Cardiac Catheterization in India.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Do ANGPTL-4 and galectin-3 reflect the severity of coronary artery disease?Therapeutic advances in cardiovascular disease · 2017
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 1 country.

Mangala RaoDepartment of Pharmacology, St. John's Medical College, Bangalore, India; Division of Clinical Research and Training, St. John's Research Institute, Bangalore, India.
Denis XavierProfessor and Head, Department of Pharmacology, St. John's Medical College, Bangalore, India; Coordinator, Division of Clinical Research and Training, St. John's Research Institute, St. John's National Academy of Health Sciences, Bangalore, India. Electronic address: denis@sjri.res.in.
Padmini DeviDepartment of Pharmacology, St. John's Medical College, Bangalore, India; Division of Clinical Research and Training, St. John's Research Institute, Bangalore, India.
Alben SigamaniDepartment of Pharmacology, St. John's Medical College, Bangalore, India; Division of Clinical Research and Training, St. John's Research Institute, Bangalore, India.
Atiya FaruquiDepartment of Pharmacology, St. John's Medical College, Bangalore, India; Division of Clinical Research and Training, St. John's Research Institute, Bangalore, India.
Rajeev GuptaDepartment of Medicine, Fortis Escorts Hospital, Jaipur, India.
Prafulla KerkarDepartment of Cardiology, KEM Hospital, Mumbai, India.
Rajendra Kumar JainDepartment of Cardiology, Krishna Institute of Medical Sciences, Secunderabad, India.
Rajnish JoshiDepartment of Medicine, All India Institute of Medical Sciences, Bhopal, India.
N ChidambaramDepartment of Medicine, Rajah Muthiah Medical College, Annamalainagar, India.
Daya Sagar RaoDepartment of Cardiology, Krishna Institute of Medical Sciences, Hyderabad, India.
S ThanikachalamCardiac Care Centre, Sri Ramachandra University, Chennai, India.
S S IyengarDepartment of Cardiology, Manipal Hospital, Bangalore, India.
Kiron VergheseDepartment of Cardiology, St.John's Medical College, Bangalore, India.
V MohanDr. Mohan's Diabetes Specialities Centre and Madras Diabetes Research Foundation, Chennai, India.
Prem PaisDivision of Clinical Research and Training, St. John's Research Institute, Bangalore, India.
St. John's National Academy of Health Sciences · INKrishna Institute of Medical Sciences · INAll India Institute of Medical Sciences Bhopal · INCollege of Medicine & JNM Hospital · INFortis Escorts Hospital · INMadras Diabetes Research Foundation · INManipal Hospital · INRajagiri Hospital · INSt.John's Medical College Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo conduct a systematic review on the prevalence, risk factors, treatments and outcomes of Coronary Artery Disease (CAD) in Indians. METHODS AND

resultsWe conducted a systematic review of studies in Indians with CAD from Jan 1969 to Oct 2012. Initial search yielded 3885 studies and after review 288 observational studies were included. The prevalence of CAD in urban areas was 2.5%-12.6% and in rural areas, 1.4%-4.6%. The prevalence of risk factors was: smoking (8.9-40.5%), hypertension (13.1-36.9%) and diabetes mellitus (0.2-24.0%). The median time to reach hospital after an MI was 360 min. In hospital rates of drug use were: antiplatelets 68%-97.9%, beta blockers 47.3%-65.8% and ACEIs 27.8-56.8%.

conclusionsIn this first systematic review of CAD in India, prevalence of risk factors is high, treatments delayed and use of evidence based treatments variable.

Indexed as

Coronary Artery DiseaseDisease ManagementRisk AssessmentHumansIndiaPrevalenceRisk FactorsCoronary artery diseaseIndiaOutcomesPrevalenceRisk factors

Identifiers

PMID26304561
PMCPMC4561784
OpenAlexW789413758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.