Evidence map›Paper›PMID 26303928›Full record

ArticleBMC ophthalmology2015

Intraocular myofibroblastoma in an infant: a case report.

Ning Hua, Jinyong Lin, Xuehan Qian, Nan Wei, Shaozhen Zhao

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ning HuaTianjin Medical University Eye Hospital, Tianjin, China. 0133_cn@sina.com.
Jinyong LinTianjin Eye Hospital, Tianjin, China. ykyylin@126.com.
Xuehan QianTianjin Medical University Eye Hospital, Tianjin, China. qianjohn@163.com.
Nan WeiTianjin Medical University Eye Hospital, Tianjin, China. dr.weinan@hotmail.com.
Shaozhen ZhaoTianjin Medical University Eye Hospital, Tianjin, China. zhaosz1997@sina.com.
Tianjin Medical University Eye Hospital · CNTianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyofibroblastoma is a benign tumor composed of spindle cells and bands of hyalinized collagen. Intraocular myofibroblastoma in infancy is rarely encountered. CASE PRESENTATION: The present study reports the case of a 4-month-old female baby with intraocular myofibroblastoma. She was suspected as corneal perforation due to the rupture of a corneal neoplasm in the right eye. The anterior segment was also involved according to the Color Doppler ultrasonography. A surgical exploration was performed and the protuberant part of the mass was resected. Conventional HE staining showed numerous spindle-shaped cells with bands of collagen beneath multilayers of well-differentiated corneal epithelia. Immunohistochemical staining demonstrated the tumor cells were strong positive for vimentin and smooth muscle actin, while negative for S-100 protein. The mass was confirmed as myofibroblastoma. After 12 month follow-up, there was no apparent growth of the tumor.

conclusionsMyofibroblastoma is a very rare type of intraocular neoplasm, which may have complicated manifestation and could be misdiagnosed as dermoid or Peter's anomaly. Histopathological and immunohistochemical staining is crucial to form a precise diagnosis.

Indexed as

ActinsBiomarkersCorneal DiseasesEye NeoplasmsFemaleHumansInfantNeoplasms, Muscle TissueS100 ProteinsUltrasonography, Doppler, ColorVimentinACTA2 protein, humanActinsBiomarkersS100 ProteinsVimentin

Identifiers

PMID26303928
PMCPMC4548843
OpenAlexW1925741347

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.