Evidence map›Paper›PMID 26303797›Full record

ArticleAntimicrobial agents and chemotherapy2015

In vitro interactions of antifungal agents and tacrolimus against Aspergillus biofilms.

Lujuan Gao, Yi Sun

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The Synergistic Effect of Tacrolimus (FK506) or Everolimus and Azoles AgainstFrontiers in cellular and infection microbiology · 2022
    Article
  6. Therapeutic Approaches for CombatingCurrent drug targets · 2022
    Review
  7. Novel Antifungal Agents and Their Activity againstJournal of fungi (Basel, Switzerland) · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lujuan GaoDepartment of Dermatology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Yi SunDepartment of Dermatology, Jingzhou Central Hospital, Jingzhou City, Hubei Province, People's Republic of China 710514760@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus biofilms were prepared from Aspergillus fumigatus, Aspergillus flavus, and Aspergillus terreus via a 96-well plate-based method, and the combined antifungal activity of tacrolimus with azoles or amphotericin B against Aspergillus biofilms was investigated via a broth microdilution checkerboard technique system. Our results suggest that combinations of tacrolimus with voriconazole or amphotericin B have synergistic inhibitory activity against Aspergillus biofilms. However, combinations of tacrolimus with itraconazole or posaconazole exhibit no synergistic or antagonistic effects.

Indexed as

Amphotericin BAntifungal AgentsAspergillusBiofilmsTacrolimusVoriconazoleAmphotericin BAntifungal AgentsTacrolimusVoriconazole

Identifiers

PMID26303797
PMCPMC4604405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.