Evidence map›Paper›PMID 26303741›Full record

Trial reportTrials2015

Effects of electroacupuncture therapy for Bell's palsy from acute stage: study protocol for a randomized controlled trial.

Zhi-dan Liu, Jiang-bo He, Si-si Guo, Zhi-xin Yang, Jun Shen, Xiao-yan Li, Wei Liang, Wei-dong Shen

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06063954 (A Randomized Trial Comparing Two Electroacupuncture Waveforms for Different Severity Groups of Bell Palsy), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06063954 nacompletednot on this mapstarted 2023, after this paper: background citation

A Randomized Trial Comparing Two Electroacupuncture Waveforms for Different Severity Groups of Bell Palsy

TypeinterventionalSponsorThe Third Affiliated hospital of Zhejiang Chinese Medical UniversityRan2023 to 2025Enrolled120ConditionsBell PalsyArmselectroacupuncture
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhi-dan LiuDepartment of Acupuncture, Baoshan Hospital of Integrated TCM and Western Medicine, Shanghai, 201999, China. liu54643@163.com.
Jiang-bo HeDepartment of Medical Imaging, Baoshan Hospital of Integrated TCM and Western Medicine, Shanghai, China. hjbxw@163.com.
Si-si GuoDepartment of Neurology, Baoshan Hospital of Integrated TCM and Western Medicine, Shanghai, 201999, China. grace_yellow@hotmail.com.
Zhi-xin YangDepartment of Gerontology, Baoshan Hospital of Integrated TCM and Western Medicine, Shanghai, 201999, China. yangzhixin931018@163.com.
Jun ShenDepartment of Neurology, Third People's Hospital, Shanghai Jiaotong University, Shanghai, 201999, China. shenjun0309@sina.com.
Xiao-yan LiDepartment of Acupuncture, Baoshan Hospital of Integrated TCM and Western Medicine, Shanghai, 201999, China. lxy_0220@163.com.
Wei LiangDepartment of Acupuncture, Baoshan Hospital of Integrated TCM and Western Medicine, Shanghai, 201999, China. bslw5660@163.com.
Wei-dong ShenDepartment of Acupuncture, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. shenweidong1018@163.com.
Integrated Chinese Medicine (China) · CNShanghai Third People's Hospital · CNShuguang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough many patients with facial paralysis have obtained benefits or completely recovered after acupuncture or electroacupuncture therapy, it is still difficult to list intuitive evidence besides evaluation using neurological function scales and a few electrophysiologic data. Hence, the aim of this study is to use more intuitive and reliable detection techniques such as facial nerve magnetic resonance imaging (MRI), nerve electromyography, and F waves to observe changes in the anatomic morphology of facial nerves and nerve conduction before and after applying acupuncture or electroacupuncture, and to verify their effectiveness by combining neurological function scales. METHODS/

designA total of 132 patients with Bell's palsy (grades III and IV in the House-Brackmann [HB] Facial Nerve Grading System) will be randomly divided into electroacupuncture, manual acupuncture, non-acupuncture, and medicine control groups. All the patients will be given electroacupuncture treatment after the acute period, except for patients in the medicine control group. The acupuncture or electroacupuncture treatments will be performed every 2 days until the patients recover or withdraw from the study. The primary outcome is analysis based on facial nerve functional scales (HB scale and Sunnybrook facial grading system), and the secondary outcome is analysis based on MRI, nerve electromyography and F-wave detection. All the patients will undergo MRI within 3 days after Bell's palsy onset for observation of the signal intensity and facial nerve swelling of the unaffected and affected sides. They will also undergo facial nerve electromyography and F-wave detection within 1 week after onset of Bell's palsy. Nerve function will be evaluated using the HB scale and Sunnybrook facial grading system at each hospital visit for treatment until the end of the study. The MRI, nerve electromyography, and F-wave detection will be performed again at 1 month after the onset of Bell's palsy.

trial registrationChinese Clinical Trials Register identifier: ChiCTR-IPR-14005730. Registered on 23 December 2014.

Indexed as

Acupuncture TherapyElectroacupunctureAcute DiseaseAdolescentAdultBell PalsyChinaClinical ProtocolsElectromyographyFacial NerveFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeural Conduction

Identifiers

PMID26303741
PMCPMC4548841
OpenAlexW2169791822

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.