Evidence map›Paper›PMID 26303634›Full record

Trial reportThe American journal of cardiology2015

Associations Between Day of Admission and Day of Surgery on Outcome and Resource Utilization in Infants With Hypoplastic Left Heart Syndrome Who Underwent Stage I Palliation (from the Single Ventricle Reconstruction Trial).

Joyce T Johnson, Lynn A Sleeper, Shan Chen, Richard G Ohye, Michael G Gaies, Ismee A Williams, Ritu Sachdeva, Jay D Pruetz, Gregory H Tatum, Deepika Thacker and 11 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Is There a Unified Etiology of Hypoplastic Left Heart Syndrome? Evaluating Genetic, Structural, and Hemodynamic Models of Disease Initiation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  2. The impact of day of surgery on the length of stay for major urological procedures.Canadian Urological Association journal = Journal de l'Association des urologues du Canada
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 17 institutions in 2 countries.

Joyce T JohnsonAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois. Electronic address: jtjohnson@luriechildrens.org.
Lynn A SleeperNew England Research Institutes, Inc., Watertown, Massachusetts.
Shan ChenNew England Research Institutes, Inc., Watertown, Massachusetts.
Richard G OhyeUniversity of Michigan Health System, Ann Arbor, Michigan.
Michael G GaiesUniversity of Michigan Health System, Ann Arbor, Michigan.
Ismee A WilliamsColumbia University Medical Center, New York City, New York.
Ritu SachdevaChildren's Healthcare of Atlanta, Emory University, Atlanta, Georgia.
Jay D PruetzChildren's Hospital Los Angeles, Los Angeles, California.
Gregory H TatumDuke Children's Hospital and Health Center, Durham, North Carolina.
Deepika ThackerNemours/Alfred L. DuPont Hospital for Children, Wilmington, Delaware.
Marissa A BrunettiChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Michele A FrommeltChildren's Hospital Wisconsin, Milwaukee, Wisconsin.
Jeffrey P JacobsAll Children's Hospital, St. Petersburg, Florida.
Joel A KirshThe Hospital for Sick Children, Toronto, Canada.
Linda M LambertUniversity of Utah at Primary Children's Hospital, Salt Lake City, Utah.
Jane W NewburgerBoston Children's Hospital, Boston, Massachusetts.
Victoria L PembertonNational Heart, Lung and Blood Institute, Bethesda, Maryland.
Sinai C ZyblewskiMedical University of South Carolina, Charleston, South Carolina.
Allison A DivanovicCincinnati Children's Hospital, Cincinnati, Ohio.
Nelangi M PintoUniversity of Utah at Primary Children's Hospital, Salt Lake City, Utah.
Pediatric Heart Network Investigators
Michigan Medicine · USNew England Research Institutes · USPrimary Children's Hospital · USBoston Children's Hospital · USChildren's Hospital of Los Angeles · USChildren's Hospital of Philadelphia · USChildren's Hospital of Wisconsin · USCincinnati Children's Hospital Medical Center · USColumbia University Irving Medical Center · USDuke Children's Hospital & Health Center · USDuPont (United States) · USEmory University · USHospital for Sick Children · CAJohns Hopkins University · USLurie Children's Hospital · USMedical University of South Carolina · USNational Heart Lung and Blood Institute · US

Funding

Pediatric Heart network DCCU10HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MILLER, JULIE ELAINE, TRACHTENBERG, FELICIA LYNN · 2011 to 2016
$44.9M
Ventricular Volumes and Varability (VVV)U01HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI SLEEPER, LYNN A · 2001 to 2010
$40.3M
Pediatric Heart Network: Follow-up of the Single Ventricle Reconstruction TrialU01HL068290 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LAI, WYMAN W · 2001 to 2010
$4.1M
Pediatric Heart Disease Network: CHOP MembershipU01HL068279 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI VETTER, VICTORIA L · 2001 to 2010
$3.7M
Randomized Therapeutic Trials in Pediatric Heart DiseaseU01HL068285 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI NEWBURGER, JANE W. · 2001 to 2010
$3.4M
Randomized Clinical Trials for Pediatric Heart DiseaseU01HL068281 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SAUL, J PHILIP · 2001 to 2010
$3.2M
Clinical and genomic responses to remote ischemic preconditioningU01HL068288 · NHLBI · HOSPITAL FOR SICK CHLDRN (TORONTO) · PI MCCRINDLE, BRIAN W · 2001 to 2010
$3.0M
Intermountain Pediatric Heart Disease Research CenterU01HL068292 · NHLBI · UNIVERSITY OF UTAH · PI MINICH, L. LUANN · 2001 to 2010
$2.7M
Randomized Trial of Nonflouroscopic Technologies in Pediatric SVT AblationU10HL109816 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI NEWBURGER, JANE W., TRIEDMAN, JOHN K · 2011 to 2015
$2.6M
The Duke-UNC-CH Pediatric Cardiology Clinical CenterU01HL068269 · NHLBI · DUKE UNIVERSITY · PI LI, JENNIFER S · 2001 to 2010
$2.6M
Pediatric Heart Network Regents of the University of MichiganU10HL109737 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GOLDBERG, CAREN S, OHYE, RICHARD G · 2011 to 2015
$2.3M
Pediatric Heart Network University of UtahU10HL109743 · NHLBI · UNIVERSITY OF UTAH · PI MINICH, L. LUANN, WILLIAMS, RICHARD VINCENT · 2011 to 2015
$2.2M
NHLBI NIH HHS HL068269NHLBI NIH HHS HL068270NHLBI NIH HHS HL068279NHLBI NIH HHS HL068281NHLBI NIH HHS HL068285NHLBI NIH HHS HL068288NHLBI NIH HHS HL068290NHLBI NIH HHS HL068292NHLBI NIH HHS HL085057NHLBI NIH HHS HL109737NHLBI NIH HHS HL109781NHLBI NIH HHS U01 HL068269NHLBI NIH HHS U01 HL068270NHLBI NIH HHS U01 HL068279NHLBI NIH HHS U01 HL068281NHLBI NIH HHS U01 HL068285NHLBI NIH HHS U01 HL068288NHLBI NIH HHS U01 HL068290NHLBI NIH HHS U01 HL068292NHLBI NIH HHS U01 HL085057NHLBI NIH HHS U10 HL068270NHLBI NIH HHS U10 HL109737NHLBI NIH HHS U10 HL109743NHLBI NIH HHS U10 HL109778NHLBI NIH HHS U10 HL109781NHLBI NIH HHS U10 HL109816
6 · The paper itself

Abstract

Newborns with hypoplastic left heart syndrome and other single right ventricular variants require substantial health care resources. Weekend acute care has been associated with worse outcomes and increased resource use in other populations but has not been studied in patients with single ventricle. Subjects of the Single Ventricle Reconstruction trial were classified by whether they had a weekend admission and by day of the week of Norwood procedure. The primary outcome was hospital length of stay (LOS); secondary outcomes included transplant-free survival, intensive care unit (ICU) LOS, and days of mechanical ventilation. The Student's t test with log transformation and the Wilcoxon rank-sum test were used to analyze associations. Admission day was categorized for 533 of 549 subjects (13% weekend). The day of the Norwood was Thursday/Friday in 39%. There was no difference in median hospital LOS, transplant-free survival, ICU LOS, or days ventilated for weekend versus non-weekend admissions. Day of the Norwood procedure was not associated with a difference in hospital LOS, transplant-free survival, ICU LOS, or days ventilated. Prenatally diagnosed infants born on the weekend had lower mean birth weight, younger gestational age, and were more likely to be intubated but did not have a difference in measured outcomes. In conclusion, in this cohort of patients with single right ventricle, neither weekend admission nor end-of-the-week Norwood procedure was associated with increased use of hospital resources or poorer outcomes. We speculate that the complex postoperative course following the Norwood procedure outweighs any impact that day of admission or operation may have on these outcomes.

Indexed as

HospitalizationNorwood ProceduresPalliative CareCohort StudiesCritical CareFemaleHealth ResourcesHeart TransplantationHumansHypoplastic Left Heart SyndromeInfantInfant, NewbornMaleRespiration, ArtificialSurvival RateTime Factors

Identifiers

PMID26303634
PMCPMC4589492
OpenAlexW2148102274

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.